A génterápia lehetóségei a sportsebészetben.

Translated title of the contribution: Gene therapy in surgical sport medicine

István Berkes, Ildikó Harbula, Akos Kynsburg, András Falus

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

The application of gene therapy to sports medicine is in its infancy, but it holds much promise as a novel procedure to improve the clinical management of sports injuries. Gene therapy will be particularly useful in initiating and accelerating the repair of cartilage, meniscus, tendon, and ligament. Several growth factors and other cytokines have been identified as important mediators of a successful healing process. Such molecules have promise as novel agents for the treatment of sports injuries, but there is presently no clinically useful way to deliver them. Gene transfer may be used to serve this purpose. Gene therapy functions as a type of local biological drug delivery system. Recent studies have shown the feasibility of transferring marker genes to synovium, chondrocytes, meniscal fibrochondrocytes, tenocytes and ligamental fibroblasts, prompting optimism about the eventual success of this approach.

Translated title of the contributionGene therapy in surgical sport medicine
Original languageHungarian
Pages (from-to)2131-2133
Number of pages3
JournalOrvosi hetilap
Volume143
Issue number37
Publication statusPublished - Sep 15 2002

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Berkes, I., Harbula, I., Kynsburg, A., & Falus, A. (2002). A génterápia lehetóségei a sportsebészetben. Orvosi hetilap, 143(37), 2131-2133.