A génterápia lehetoségei hasnyálmirigyrá kban

Translated title of the contribution: Gene therapy in pancreatic cancer

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Pancreatic cancer is the fifth cause of cancer death in the developed world. It is a highly malignant disease, characterised by aggressive local spread and early locoregional and hepatic metastasis. Surgery offers the only prospect of long-term survival, but the resecability ratio is very low at the time of diagnosis. Conventional chemo- and radiotherapy are relatively ineffective, that is why development of newer therapeutic alternatives are encouraged. Gene therapy came into the lime-light of interest. Authors discuss the fundamental scientific principle and clinical experience in connection with gene therapy of pancreatic cancer. Different targets include antisense strategies, gene-replacement, gene-directed prodrug activation therapy, promoter gene strategies, as well as oncolytic viruses.

Translated title of the contributionGene therapy in pancreatic cancer
Original languageHungarian
Pages (from-to)211-215
Number of pages5
JournalOrvosi hetilap
Volume145
Issue number5
Publication statusPublished - Feb 1 2004

ASJC Scopus subject areas

  • Medicine(all)

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