Gas chromatography of some prostaglandins

Z. Juvancz, M. Vajda, V. Simonidesz

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The synthetic prostaglandin F (PG), used as an ovulation regulator, and abortion inducer, is contaminated with its Δ5-trans isomer. The ratio of the isomers was measured by capillary GC. The prostaglandin I2 (PGI2), a blood platelet aggregation inhibitor, easily decomposes to 6-ketoprostaglandin F (6-keto PG). Their ratio was measured by packed column GC. An unexpected, instantaneous methanol cleavage was observed during the GC analysis of the methyl ketal derivative of 6-keto PG, forming a mixture of PGI2 and Δ6-prostaglandin I1 (Δ6-PGI1).

Original languageEnglish
Pages (from-to)285-287
Number of pages3
JournalChromatographia
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 1984

Fingerprint

Epoprostenol
Isomers
Gas chromatography
Gas Chromatography
Prostaglandins
Synthetic Prostaglandins
Dinoprost
Platelet Aggregation Inhibitors
Ovulation
Methanol
Derivatives

Keywords

  • Gas chromatography
  • Prostaglandins isomers

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry

Cite this

Gas chromatography of some prostaglandins. / Juvancz, Z.; Vajda, M.; Simonidesz, V.

In: Chromatographia, Vol. 19, No. 1, 01.1984, p. 285-287.

Research output: Contribution to journalArticle

Juvancz, Z, Vajda, M & Simonidesz, V 1984, 'Gas chromatography of some prostaglandins', Chromatographia, vol. 19, no. 1, pp. 285-287. https://doi.org/10.1007/BF02687755
Juvancz, Z. ; Vajda, M. ; Simonidesz, V. / Gas chromatography of some prostaglandins. In: Chromatographia. 1984 ; Vol. 19, No. 1. pp. 285-287.
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