Galanin-like immunoreactive nerve elements in the small intestine of the rat. An electron microscopic immunocytochemical study

E. Fehér, Geoffrey Burnstock

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Nerve cell bodies and fibres showing galanin-like immunoreactivity have been demonstrated in rat small intestine using immunocytochemistry. Immunoreactive cell bodies were observed in both the myenteric and the submucous plexuses. Immunoreactive nerve fibres were observed in all layers of the small intestine, especially in both plexuses and in the inner circular muscle layer. The immunoreactive nerve processes were found in close association (sometimes separated by less than 40 nm) with smooth muscle cells. These terminals contained both agranular vesicles (30-40 nm) and large granular vesicles (80-120 nm). Immunoreactive nerve fibres were sometimes seen in perivascular plexuses. It is concluded that, in rat small intestine, neurones expressing galanin-like immunoreactivity project to several different sites and may participate in a number of mechanisms, including the regulation of smooth muscle activity, mucosal cell secretion and blood flow; galanin may also be involved in interneuronal activity.

Original languageEnglish
Pages (from-to)137-142
Number of pages6
JournalNeuroscience Letters
Volume92
Issue number2
DOIs
Publication statusPublished - Oct 5 1988

Fingerprint

Galanin
Nerve Fibers
Small Intestine
Electrons
Submucous Plexus
Neurons
Myenteric Plexus
Smooth Muscle Myocytes
Smooth Muscle
Blood Cells
Immunohistochemistry
Muscles
Cell Body

Keywords

  • Autonomic nerve
  • Galanin
  • Immunocytochemistry
  • Small intestine

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Galanin-like immunoreactive nerve elements in the small intestine of the rat. An electron microscopic immunocytochemical study. / Fehér, E.; Burnstock, Geoffrey.

In: Neuroscience Letters, Vol. 92, No. 2, 05.10.1988, p. 137-142.

Research output: Contribution to journalArticle

@article{0bd70df5f0e44af7a27c4327f1d0e6a2,
title = "Galanin-like immunoreactive nerve elements in the small intestine of the rat. An electron microscopic immunocytochemical study",
abstract = "Nerve cell bodies and fibres showing galanin-like immunoreactivity have been demonstrated in rat small intestine using immunocytochemistry. Immunoreactive cell bodies were observed in both the myenteric and the submucous plexuses. Immunoreactive nerve fibres were observed in all layers of the small intestine, especially in both plexuses and in the inner circular muscle layer. The immunoreactive nerve processes were found in close association (sometimes separated by less than 40 nm) with smooth muscle cells. These terminals contained both agranular vesicles (30-40 nm) and large granular vesicles (80-120 nm). Immunoreactive nerve fibres were sometimes seen in perivascular plexuses. It is concluded that, in rat small intestine, neurones expressing galanin-like immunoreactivity project to several different sites and may participate in a number of mechanisms, including the regulation of smooth muscle activity, mucosal cell secretion and blood flow; galanin may also be involved in interneuronal activity.",
keywords = "Autonomic nerve, Galanin, Immunocytochemistry, Small intestine",
author = "E. Feh{\'e}r and Geoffrey Burnstock",
year = "1988",
month = "10",
day = "5",
doi = "10.1016/0304-3940(88)90049-3",
language = "English",
volume = "92",
pages = "137--142",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Galanin-like immunoreactive nerve elements in the small intestine of the rat. An electron microscopic immunocytochemical study

AU - Fehér, E.

AU - Burnstock, Geoffrey

PY - 1988/10/5

Y1 - 1988/10/5

N2 - Nerve cell bodies and fibres showing galanin-like immunoreactivity have been demonstrated in rat small intestine using immunocytochemistry. Immunoreactive cell bodies were observed in both the myenteric and the submucous plexuses. Immunoreactive nerve fibres were observed in all layers of the small intestine, especially in both plexuses and in the inner circular muscle layer. The immunoreactive nerve processes were found in close association (sometimes separated by less than 40 nm) with smooth muscle cells. These terminals contained both agranular vesicles (30-40 nm) and large granular vesicles (80-120 nm). Immunoreactive nerve fibres were sometimes seen in perivascular plexuses. It is concluded that, in rat small intestine, neurones expressing galanin-like immunoreactivity project to several different sites and may participate in a number of mechanisms, including the regulation of smooth muscle activity, mucosal cell secretion and blood flow; galanin may also be involved in interneuronal activity.

AB - Nerve cell bodies and fibres showing galanin-like immunoreactivity have been demonstrated in rat small intestine using immunocytochemistry. Immunoreactive cell bodies were observed in both the myenteric and the submucous plexuses. Immunoreactive nerve fibres were observed in all layers of the small intestine, especially in both plexuses and in the inner circular muscle layer. The immunoreactive nerve processes were found in close association (sometimes separated by less than 40 nm) with smooth muscle cells. These terminals contained both agranular vesicles (30-40 nm) and large granular vesicles (80-120 nm). Immunoreactive nerve fibres were sometimes seen in perivascular plexuses. It is concluded that, in rat small intestine, neurones expressing galanin-like immunoreactivity project to several different sites and may participate in a number of mechanisms, including the regulation of smooth muscle activity, mucosal cell secretion and blood flow; galanin may also be involved in interneuronal activity.

KW - Autonomic nerve

KW - Galanin

KW - Immunocytochemistry

KW - Small intestine

UR - http://www.scopus.com/inward/record.url?scp=0023741016&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023741016&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(88)90049-3

DO - 10.1016/0304-3940(88)90049-3

M3 - Article

C2 - 2460807

AN - SCOPUS:0023741016

VL - 92

SP - 137

EP - 142

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 2

ER -