GABA signalling during development: New data and old questions

Patricia Varju, Zoya Katarova, E. Madarász, Gábor Szabó

Research output: Contribution to journalArticle

110 Citations (Scopus)

Abstract

In addition to being the major inhibitory neurotransmitter, γ-aminobutyric acid (GABA) is thought to play a morphogenetic role in embryonic development. During the last decade, considerable progress has been made in elucidating the molecular mechanisms involved in GABA synthesis and biological action. The present review is an attempt to summarise recent results on the ontogeny of the different components of embryonic GABA signalling with an emphasis on the synthesis of GABA by different molecular forms of glutamic acid decarboxylase (GAD).

Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalCell and Tissue Research
Volume305
Issue number2
DOIs
Publication statusPublished - 2001

Fingerprint

gamma-Aminobutyric Acid
Aminobutyrates
Glutamate Decarboxylase
Embryonic Development
Neurotransmitter Agents

Keywords

  • Embryonic development
  • GAD
  • Neuronal differentiation
  • Trophic action

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology

Cite this

GABA signalling during development : New data and old questions. / Varju, Patricia; Katarova, Zoya; Madarász, E.; Szabó, Gábor.

In: Cell and Tissue Research, Vol. 305, No. 2, 2001, p. 239-246.

Research output: Contribution to journalArticle

Varju, Patricia ; Katarova, Zoya ; Madarász, E. ; Szabó, Gábor. / GABA signalling during development : New data and old questions. In: Cell and Tissue Research. 2001 ; Vol. 305, No. 2. pp. 239-246.
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