GABA-immunoreactive neurons in the dorsal lateral geniculate nucleus of the rat: characterisation by combined Golgi-impregnation and immunocytochemistry

P. L A Gabbott, J. Somogyi, M. G. Stewart, J. Hámori

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Identified neurons in the dorsal lateral geniculate nucleus (dLGN) of the rat were studied using a Golgi/EM procedure in combination with post-embedding GABA immunocytochemistry. The results of this investigation identify clearly the GABA-immunoreactive nature of the two morphologically] distinct neuronal populations found within the rat dLGN - thalamocortical relay cells are GABA-immunonegative whilst the putative 'interneurons' are GABA-immunopositive. This immunocytochemical evidence strongly suggests that 'interneurons' synthesize and use GABA to mediate their local inhibitory synaptic mechanisms within the dLGN of the rat.

Original languageEnglish
Pages (from-to)311-322
Number of pages12
JournalExperimental Brain Research
Volume61
Issue number2
DOIs
Publication statusPublished - Jan 1986

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Geniculate Bodies
GABAergic Neurons
gamma-Aminobutyric Acid
Immunohistochemistry
Interneurons
Neurons
Population

Keywords

  • Dorsal lateral geniculate nucleus (dLGN)
  • GABA immunocytochemistry
  • Golgi/EM
  • Interneurons
  • Rat

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

GABA-immunoreactive neurons in the dorsal lateral geniculate nucleus of the rat : characterisation by combined Golgi-impregnation and immunocytochemistry. / Gabbott, P. L A; Somogyi, J.; Stewart, M. G.; Hámori, J.

In: Experimental Brain Research, Vol. 61, No. 2, 01.1986, p. 311-322.

Research output: Contribution to journalArticle

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