Further insights into coronary debulking: the EUROCARE trial of directional atherectomy and the PACT trial of pullback atherectomy.

A. Thury, G. Van Langenhove, A. J. Wardeh, D. P. Foley, P. W. Serruys

Research output: Contribution to journalReview article


Although the principle of reducing plaque load in the coronary artery remains very appealing, clinical benefit from debulking devices has not been demonstrated unequivocally. Other approaches to prevent restenosis had been the application of various pharmacological agents. Unfortunately, the majority of clinical studies have not reproduced the promising results observed in the experimental laboratories. New frontiers in improving atherectomy devices and in optimizing concomitant medical treatment are currently being explored. We report on the EUROCARE trial investigating the possible benefit of carvedilol after coronary atherectomy, and the Pullback Atherectomy (PAC) pilot trial using a novel atherectomy device.

Original languageEnglish
Pages (from-to)185-192
Number of pages8
JournalSeminars in interventional cardiology : SIIC
Issue number4
Publication statusPublished - Dec 2000


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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