Further Evidence for the Utility of Electrophysiological Methods for the Detection of Subclinical Stage Retinal and Optic Nerve Involvement in Diabetes

Klára Deák, Imre Fejes, Márta Janáky, Tamás Várkonyi, György Benedek, Gábor Braunitzer

Research output: Contribution to journalArticle

4 Citations (Scopus)


Objective: To assess the utility of visual electrophysiological methods, visual evoked potentials (VEPs) and pattern electroretinograms (PERGs) were recorded for the detection of subclinical optic nerve and retinal involvement in patients with diabetes mellitus. Subjects and Methods: The data of 63 patients (126 eyes) with no vascular retinopathy or optic neuropathy were retrospectively analyzed. The patients were divided into polyneuropathic/nonpolyneuropathic groups to differentiate between early and late subclinical stages. The recorded parameters were compared with local reference values. Results: 116 eyes (92%) had VEP and 76 (60%) had PERG abnormalities. The most frequent alteration was latency delay, but waveform and amplitude irregularities were also observed. The simultaneous use of the two methods allowed us to differentiate abnormal VEPs of purely optic nerve origin from those reflecting retinal involvement. Conclusions: We suggest that regular electrophysiological screening should receive more attention in the ophthalmological care of diabetic patients.

Original languageEnglish
Pages (from-to)282-285
Number of pages4
JournalMedical Principles and Practice
Issue number3
Publication statusPublished - Apr 1 2016



  • Diabetes mellitus
  • Neuropathy
  • Pattern electroretinography
  • Visual evoked potentials

ASJC Scopus subject areas

  • Medicine(all)

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