Further characterization of Hungarian acatalasemia by Hinf1 polymorphism of catalase gene

L. Goth, B. N. Alizadeh, H. H. Sussman

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

An Hinf1 associated restriction length polymorphism pattern is reported for the catalase gene of Hungarian normocatalasemic individuals and acatalasemic patients. The 2.4-kb pCAT 10 probe revealed 9 bands (2.1, 1.5, 1.2, 1.1, 0.9, 0.8, 0.6, 0.5 and 0.4 kb) with 9 distinct patterns for the controls. The same patterns were detected for the Hungarian acatalasemic patients. The examination of the A to T mutation of the Hungarian acatalasemic patients and their relatives at position -21 in the flanking region with Hinf1 polymorphism could not reveal any difference between the acatalasemic and the normocatalasemic catalase gene.

Original languageEnglish
Pages (from-to)156-159
Number of pages4
JournalEnzyme and Protein
Volume47
Issue number3
DOIs
Publication statusPublished - Jan 1 1993

Keywords

  • Hinf1 polymorphism
  • RFLP
  • acatalasemia in Hungary
  • pCAT 10 probe, 2.4-kb

ASJC Scopus subject areas

  • Biochemistry

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