Further characterization of degenerated human cartilage with differential scanning calorimetry

K. Tóth, G. Sohár, E. Pallagi, P. Szabó-Révész

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A limited number of papers have been published before on the subject of thermal analysis of normal and degenerative human hyaline cartilage. They have concluded that structural manifestation of osteoarthritis appears as a remarkable change of thermal stability of hyaline cartilage samples. The reported data on the calorimetric enthalpy changes proved to be inconsistent. Previous thermoanalytical studies used cadaver samples for the investigation as normal human hyaline cartilage. All samples that were extracted for this study were obtained during live surgeries. A new protocol had to be established before the detailed investigation could be performed. With the rise of temperature, an endothermic reaction was observed in all cases. The enthalpy change of the process initiated by the temperature change showed marked difference between the normal and pathological groups. The use of differential scanning calorimetry as part of thermal analysis was a reliable method for differentiating normal hyaline cartilage from degenerated samples.

Original languageEnglish
Pages (from-to)75-77
Number of pages3
JournalThermochimica Acta
Volume464
Issue number1-2
DOIs
Publication statusPublished - Nov 25 2007

Keywords

  • DSC
  • Enthalpy
  • Human hyaline cartilage
  • Osteoarthritis

ASJC Scopus subject areas

  • Instrumentation
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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