Functionalization of the estrone skeleton via homogeneous coupling and hydroformylation reactions

L. Kollár, R. Skoda-Földes, Sándor Mahó, Zoltán Tuba

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The estrone triflate (3-trifluoromethylsulfonate-estra-1,3,5(10)-triene-17-one) was vinylated by use of vinyltributyltin in the presence of palladium catalysts. The rhodium- and platinum-catalysed hydroformylation of the vinylated aromatic steroid gave the pure epimer 3-(2′-formylethyl)-estra-1,3,5(10)-triene-17-one.

Original languageEnglish
Pages (from-to)159-162
Number of pages4
JournalJournal of Organometallic Chemistry
Volume453
Issue number1
DOIs
Publication statusPublished - Jun 29 1993

Fingerprint

trienes
Hydroformylation
Rhodium
Estrone
Palladium
Platinum
musculoskeletal system
Skeleton
Steroids
steroids
Catalysts
rhodium
palladium
platinum
catalysts
vinyltributylstannane

ASJC Scopus subject areas

  • Biochemistry
  • Chemical Engineering (miscellaneous)
  • Inorganic Chemistry
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Science (miscellaneous)
  • Materials Chemistry

Cite this

Functionalization of the estrone skeleton via homogeneous coupling and hydroformylation reactions. / Kollár, L.; Skoda-Földes, R.; Mahó, Sándor; Tuba, Zoltán.

In: Journal of Organometallic Chemistry, Vol. 453, No. 1, 29.06.1993, p. 159-162.

Research output: Contribution to journalArticle

@article{ef14401f2980440fb920babf59914887,
title = "Functionalization of the estrone skeleton via homogeneous coupling and hydroformylation reactions",
abstract = "The estrone triflate (3-trifluoromethylsulfonate-estra-1,3,5(10)-triene-17-one) was vinylated by use of vinyltributyltin in the presence of palladium catalysts. The rhodium- and platinum-catalysed hydroformylation of the vinylated aromatic steroid gave the pure epimer 3-(2′-formylethyl)-estra-1,3,5(10)-triene-17-one.",
author = "L. Koll{\'a}r and R. Skoda-F{\"o}ldes and S{\'a}ndor Mah{\'o} and Zolt{\'a}n Tuba",
year = "1993",
month = "6",
day = "29",
doi = "10.1016/0022-328X(93)80342-9",
language = "English",
volume = "453",
pages = "159--162",
journal = "Journal of Organometallic Chemistry",
issn = "0022-328X",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Functionalization of the estrone skeleton via homogeneous coupling and hydroformylation reactions

AU - Kollár, L.

AU - Skoda-Földes, R.

AU - Mahó, Sándor

AU - Tuba, Zoltán

PY - 1993/6/29

Y1 - 1993/6/29

N2 - The estrone triflate (3-trifluoromethylsulfonate-estra-1,3,5(10)-triene-17-one) was vinylated by use of vinyltributyltin in the presence of palladium catalysts. The rhodium- and platinum-catalysed hydroformylation of the vinylated aromatic steroid gave the pure epimer 3-(2′-formylethyl)-estra-1,3,5(10)-triene-17-one.

AB - The estrone triflate (3-trifluoromethylsulfonate-estra-1,3,5(10)-triene-17-one) was vinylated by use of vinyltributyltin in the presence of palladium catalysts. The rhodium- and platinum-catalysed hydroformylation of the vinylated aromatic steroid gave the pure epimer 3-(2′-formylethyl)-estra-1,3,5(10)-triene-17-one.

UR - http://www.scopus.com/inward/record.url?scp=8244258678&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8244258678&partnerID=8YFLogxK

U2 - 10.1016/0022-328X(93)80342-9

DO - 10.1016/0022-328X(93)80342-9

M3 - Article

VL - 453

SP - 159

EP - 162

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

SN - 0022-328X

IS - 1

ER -