Functional variations in parenchymal microvascular systems within the brain

Joseph Fenstermacher, Hiroyuki Nakata, Atsushi Tajima, Shinn‐Zong ‐Z Lin, Tadahiro Otsuka, Virgil Acuff, Ling Wei, Daniel Bereczki

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14 Citations (Scopus)

Abstract

Variations in microvascular system functions were observed among a number of brain areas. The rates of local blood flow varied 18‐fold among areas and were extremely high in neuroendocrine structures. Marked differences in blood flow were also found within some brain structures. The volume of radiolabeled blood in perfused parenchymal micro‐vessels ranged from 5 to 70 μl/g and correlated closely with local cerebral blood flow. The hematocrits within parenchymal microvessels were 45–75% of the arterial hematocrit, which indicates that red cells more rapidly traverse brain microvessels than do plasma proteins. The mean transit times of blood through parenchymal microvessels were extremely short and ranged from 0.3 to 0.6 s. © 1991 Academic Press, Inc.

Original languageEnglish
Pages (from-to)217-220
Number of pages4
JournalMagnetic Resonance in Medicine
Volume19
Issue number2
DOIs
Publication statusPublished - Jun 1991

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Fenstermacher, J., Nakata, H., Tajima, A., Lin, SZ. Z., Otsuka, T., Acuff, V., Wei, L., & Bereczki, D. (1991). Functional variations in parenchymal microvascular systems within the brain. Magnetic Resonance in Medicine, 19(2), 217-220. https://doi.org/10.1002/mrm.1910190205