Functional pathology of brain development caused by food contaminant fumonisin B 1

Péter Banczerowski, Ildikó Világi, Petra Varró, Zsuzsanna Sófalvy, Ilona Banczerowski-Pelyhe

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Effects of prenatal exposition to fumonisin B1 (FB1) on in vitro brain slice bioelectric activity was investigated in the first generation offspring of FB1 treated pregnant rats. This is the first study to use in vitro rat cortex slices as biosensors monitoring pathologic bioelectric activity changes (an epilepsy model) in offspring after FB 1 exposition of pregnant rats, and providing evidence for functional anomalies of neurodevelopmental origin.

Original languageEnglish
Pages (from-to)1891-1894
Number of pages4
JournalCereal Research Communications
Volume36
Issue numberSUPPL. 5
DOIs
Publication statusPublished - Dec 1 2008

Keywords

  • Developmental toxicity
  • Epilepsy model
  • Fumonisin B mycotoxin
  • In vitro biotests
  • Rat cortex slice

ASJC Scopus subject areas

  • Physiology
  • Agronomy and Crop Science
  • Genetics

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