Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis

A. Ponyi, G. Borgulya, T. Constantin, A. Váncsa, L. Gergely, K. Dankó

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Objectives. To present the outcome of patients with idiopathic inflammatory myositis, focusing on functional ability and quality of life. Methods. Analysis was performed using data from 105 adult patients with definitive polymyositis, dermatomyositis or overlap myositis, who were followed up at a single centre. The diagnosis was made between 1979 and 2000 based on Bohan and Peter's criteria. Functional ability was assessed after a minimum follow-up of 3 yr with the Health Assessment Questionnaire Disability Index (HAQDI) and quality of life was measured with the Short Form 36-item questionnaire (SF-36). Results. Fifteen patients in our cohort died and 87 participated in the evaluation of functional outcome. Functional ability after a median follow-up of 107.1 months (range 36.4-273.3) was heterogeneous. The median HAQDI score was 0.875 (range 0-2.875). Polyphasic or chronic-progressive disease course, osteoporosis and long-term follow-up were predictive of higher HAQDI scores. In terms of quality of life, significant differences from population norms were shown in all domains of the SF-36. There were no significant differences in the SF-36 scores among the patients according to clinicopathological subset or disease course. Conclusions. Although the mortality of our cohort was favourable, myositis continues to have a great impact on life in the medium and long term. The present work indicates that myositis patients have a significantly poorer quality of life than the normal population, but there was no difference among the patients according to clinicopathological subsets.

Original languageEnglish
Pages (from-to)83-88
Number of pages6
JournalRheumatology
Volume44
Issue number1
DOIs
Publication statusPublished - Jan 2005

Fingerprint

Myositis
Quality of Life
Health
Dermatomyositis
Population
Osteoporosis
Chronic Disease
Mortality
Surveys and Questionnaires

Keywords

  • Dermatomyositis
  • Outcome
  • Overlap myositis
  • Polymyositis
  • Quality of life

ASJC Scopus subject areas

  • Neuroscience(all)
  • Rheumatology

Cite this

Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis. / Ponyi, A.; Borgulya, G.; Constantin, T.; Váncsa, A.; Gergely, L.; Dankó, K.

In: Rheumatology, Vol. 44, No. 1, 01.2005, p. 83-88.

Research output: Contribution to journalArticle

@article{2e5ae2952d8a42f98e3cc7d9187f7ba6,
title = "Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis",
abstract = "Objectives. To present the outcome of patients with idiopathic inflammatory myositis, focusing on functional ability and quality of life. Methods. Analysis was performed using data from 105 adult patients with definitive polymyositis, dermatomyositis or overlap myositis, who were followed up at a single centre. The diagnosis was made between 1979 and 2000 based on Bohan and Peter's criteria. Functional ability was assessed after a minimum follow-up of 3 yr with the Health Assessment Questionnaire Disability Index (HAQDI) and quality of life was measured with the Short Form 36-item questionnaire (SF-36). Results. Fifteen patients in our cohort died and 87 participated in the evaluation of functional outcome. Functional ability after a median follow-up of 107.1 months (range 36.4-273.3) was heterogeneous. The median HAQDI score was 0.875 (range 0-2.875). Polyphasic or chronic-progressive disease course, osteoporosis and long-term follow-up were predictive of higher HAQDI scores. In terms of quality of life, significant differences from population norms were shown in all domains of the SF-36. There were no significant differences in the SF-36 scores among the patients according to clinicopathological subset or disease course. Conclusions. Although the mortality of our cohort was favourable, myositis continues to have a great impact on life in the medium and long term. The present work indicates that myositis patients have a significantly poorer quality of life than the normal population, but there was no difference among the patients according to clinicopathological subsets.",
keywords = "Dermatomyositis, Outcome, Overlap myositis, Polymyositis, Quality of life",
author = "A. Ponyi and G. Borgulya and T. Constantin and A. V{\'a}ncsa and L. Gergely and K. Dank{\'o}",
year = "2005",
month = "1",
doi = "10.1093/rheumatology/keh404",
language = "English",
volume = "44",
pages = "83--88",
journal = "Rheumatology",
issn = "1462-0324",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis

AU - Ponyi, A.

AU - Borgulya, G.

AU - Constantin, T.

AU - Váncsa, A.

AU - Gergely, L.

AU - Dankó, K.

PY - 2005/1

Y1 - 2005/1

N2 - Objectives. To present the outcome of patients with idiopathic inflammatory myositis, focusing on functional ability and quality of life. Methods. Analysis was performed using data from 105 adult patients with definitive polymyositis, dermatomyositis or overlap myositis, who were followed up at a single centre. The diagnosis was made between 1979 and 2000 based on Bohan and Peter's criteria. Functional ability was assessed after a minimum follow-up of 3 yr with the Health Assessment Questionnaire Disability Index (HAQDI) and quality of life was measured with the Short Form 36-item questionnaire (SF-36). Results. Fifteen patients in our cohort died and 87 participated in the evaluation of functional outcome. Functional ability after a median follow-up of 107.1 months (range 36.4-273.3) was heterogeneous. The median HAQDI score was 0.875 (range 0-2.875). Polyphasic or chronic-progressive disease course, osteoporosis and long-term follow-up were predictive of higher HAQDI scores. In terms of quality of life, significant differences from population norms were shown in all domains of the SF-36. There were no significant differences in the SF-36 scores among the patients according to clinicopathological subset or disease course. Conclusions. Although the mortality of our cohort was favourable, myositis continues to have a great impact on life in the medium and long term. The present work indicates that myositis patients have a significantly poorer quality of life than the normal population, but there was no difference among the patients according to clinicopathological subsets.

AB - Objectives. To present the outcome of patients with idiopathic inflammatory myositis, focusing on functional ability and quality of life. Methods. Analysis was performed using data from 105 adult patients with definitive polymyositis, dermatomyositis or overlap myositis, who were followed up at a single centre. The diagnosis was made between 1979 and 2000 based on Bohan and Peter's criteria. Functional ability was assessed after a minimum follow-up of 3 yr with the Health Assessment Questionnaire Disability Index (HAQDI) and quality of life was measured with the Short Form 36-item questionnaire (SF-36). Results. Fifteen patients in our cohort died and 87 participated in the evaluation of functional outcome. Functional ability after a median follow-up of 107.1 months (range 36.4-273.3) was heterogeneous. The median HAQDI score was 0.875 (range 0-2.875). Polyphasic or chronic-progressive disease course, osteoporosis and long-term follow-up were predictive of higher HAQDI scores. In terms of quality of life, significant differences from population norms were shown in all domains of the SF-36. There were no significant differences in the SF-36 scores among the patients according to clinicopathological subset or disease course. Conclusions. Although the mortality of our cohort was favourable, myositis continues to have a great impact on life in the medium and long term. The present work indicates that myositis patients have a significantly poorer quality of life than the normal population, but there was no difference among the patients according to clinicopathological subsets.

KW - Dermatomyositis

KW - Outcome

KW - Overlap myositis

KW - Polymyositis

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=12344327640&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=12344327640&partnerID=8YFLogxK

U2 - 10.1093/rheumatology/keh404

DO - 10.1093/rheumatology/keh404

M3 - Article

VL - 44

SP - 83

EP - 88

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 1

ER -