Fully on-line TLC/HPTLC with diode-array detection and continuous development. Part 1: Description of the method and basic possibilities

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Abstract

A novel liquid chromatographic technique, fully on-line TLC/HPTLC, is described. Although no forces other than capillary action are used, and evaporation of the mobile phase induces the linear mobile phase velocity, the method can be regarded as a type of forced-flow chromatography. The method integrates the idea of the continuous development, continuous-flow TLC, and diodearray detection. This paper describes the principle of the method, the design of the prototype apparatus, and the fundamental advantages of the novel technique.

Original languageEnglish
Pages (from-to)454-457
Number of pages4
JournalJournal of Planar Chromatography - Modern TLC
Volume15
Issue number6
DOIs
Publication statusPublished - Nov 1 2002

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Keywords

  • Continuous development
  • Diode-array detection
  • Forced-flow separation
  • Fully on-line HPTLC
  • On-line detection
  • On-line injection

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry

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