From the germinal cells to the newborn animal: The transmission of genes and life through the generations

P. V. Drion, O. Szenci, F. Ectors, D. Wirth, Zs Perényi, P. Muller, J. F. Beckers

Research output: Contribution to journalArticle

Abstract

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most spectacular manipulations are cloning and transgenesis. This review focuses on the early appearance of germinal cell precursors and the long-standing fate of gametes in mammals. The evident complexity and long-term programming of events in gametes and early embryos explain part of the difficulties encountered during the development of in vitro and in vivo methods such as multiple ovulation and embryo transfer (MOET), oestrus synchronisation, ovulation induction, superovulation, in vitro maturation and fertilisation, cryopreservation, transgenesis, nuclear transfer and cloning) and the occurrence of unexpected alterations of development, e.g. embryonic or fetal mortality, large-weight newborn syndrome and other dysregulations in imprinting or DNA transmission.

Original languageEnglish
Pages (from-to)371-384
Number of pages14
JournalActa Veterinaria Hungarica
Volume51
Issue number3
DOIs
Publication statusPublished - 2003

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Newborn Animals
Gene Transfer Techniques
Fertilization in Vitro
fertilization (reproduction)
Germ Cells
ovulation
Organism Cloning
molecular cloning
germ cells
neonates
Embryonic Structures
Estrus Synchronization
Superovulation
Fetal Mortality
genomic imprinting
estrus synchronization
superovulation
Ovulation Induction
embryo culture
Embryo Transfer

Keywords

  • Cattle
  • Follicular growth
  • Germinal cells
  • In vitro methods

ASJC Scopus subject areas

  • veterinary(all)

Cite this

From the germinal cells to the newborn animal : The transmission of genes and life through the generations. / Drion, P. V.; Szenci, O.; Ectors, F.; Wirth, D.; Perényi, Zs; Muller, P.; Beckers, J. F.

In: Acta Veterinaria Hungarica, Vol. 51, No. 3, 2003, p. 371-384.

Research output: Contribution to journalArticle

Drion, P. V. ; Szenci, O. ; Ectors, F. ; Wirth, D. ; Perényi, Zs ; Muller, P. ; Beckers, J. F. / From the germinal cells to the newborn animal : The transmission of genes and life through the generations. In: Acta Veterinaria Hungarica. 2003 ; Vol. 51, No. 3. pp. 371-384.
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