A Leiden-mutáció gyakorisága HELLP szindrómával szövodött terhességekben

Translated title of the contribution: Frequency of Leiden mutation in pregnancies complicated with HELLP syndrome

Petronella Hupyczi, B. Nagy, Gábor Szabó, Barbara Rigó, I. Sziller, Z. Papp

Research output: Contribution to journalArticle

Abstract

HELLP syndrome is a serious form of preeclampsia. One of the most common genetic causes of thrombosis is the presence of Factor V Leiden mutation. We determined the occurrence of the mutation in a group of 103 healthy women, in 69 patients having preeclampsia and 54 women having HELLP syndrome. For determination of factor V Leiden mutation the quantitative real-time PCR method was used. We found the frequency of Leiden mutation in heterozygotic form to be 4,85% in the normal healthy group, 14,5% in the preeclamptic and 16,7% in the group with HELLP syndrome (p

Original languageHungarian
Pages (from-to)289-295
Number of pages7
JournalMagyar Noorvosok Lapja
Volume69
Issue number4
Publication statusPublished - 2006

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HELLP Syndrome
Mutation Rate
Pre-Eclampsia
Pregnancy
Mutation
Real-Time Polymerase Chain Reaction
Thrombosis
factor V Leiden

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

A Leiden-mutáció gyakorisága HELLP szindrómával szövodött terhességekben. / Hupyczi, Petronella; Nagy, B.; Szabó, Gábor; Rigó, Barbara; Sziller, I.; Papp, Z.

In: Magyar Noorvosok Lapja, Vol. 69, No. 4, 2006, p. 289-295.

Research output: Contribution to journalArticle

Hupyczi, Petronella ; Nagy, B. ; Szabó, Gábor ; Rigó, Barbara ; Sziller, I. ; Papp, Z. / A Leiden-mutáció gyakorisága HELLP szindrómával szövodött terhességekben. In: Magyar Noorvosok Lapja. 2006 ; Vol. 69, No. 4. pp. 289-295.
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