Szomszédos csigolyatörések elo′fordulása percutan vertebroplastica után

Translated title of the contribution: Frequency of adjacent vertebral fractures following percutaneous vertebroplasty

Zsolt Kulcsár, Miklós Marosfoi, Zsolt Berentei, Róbert Veres, István Nyáry, István Szikora

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction and aims: Percutaneous vertebroplasty (PVP) proved to be very effective in the treatment of pain caused by osteoporotic vertebral compression fractures. A certain proportion of patients, however, suffer a new fracture after treatment. our purpose was to analyze the frequency of new fractures, and to estimate the causative role of PVP in the treated population. Methods: The retrospective study reviewed all consecutive patients treated with PVP for osteoporotic compression fractures during a 5.5 years period. The study group comprised those patients, who suffered a new fracture during the follow up. The primary endpoint was the frequency of new fractures. The secondary endpoint was the occurrence of new fractures in a timeframe of 90 days after treatment that were adjacent to the previously treated segments. The causative role of PVP was estimated to be the highest in this subgroup. Results: Altogether 396 consecutive patients were treated with PVP for osteoporotic compression fractures. Mean age was 68+11 years, and 23% of the population was male. The study group comprised 73 patients (18.4%). In this subgroup the patients had an average of 3.8 vertebral fractures. After PVP, adjacent fractures were significantly more likely, than distal fractures. Altogether 44 patients (11% of the entire population) suffered an adjacent fracture in 90 days after PVP. In this group there were significantly less male patients as compared to the entire population. Conclusions: After PVP almost every fifth patient is at risk for developing a new fracture, however, it is likely to be related to the vertebral augmentation in every tenth subject only. Female patients with severe osteoporosis are probably facing the highest risk for developing new fractures.

Original languageHungarian
Pages (from-to)1744-1748
Number of pages5
JournalOrvosi Hetilap
Volume150
Issue number37
DOIs
Publication statusPublished - Sep 1 2009

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Vertebroplasty
Compression Fractures
Osteoporotic Fractures
Population
Osteoporosis
Therapeutics
Retrospective Studies

ASJC Scopus subject areas

  • Medicine(all)

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Szomszédos csigolyatörések elo′fordulása percutan vertebroplastica után. / Kulcsár, Zsolt; Marosfoi, Miklós; Berentei, Zsolt; Veres, Róbert; Nyáry, István; Szikora, István.

In: Orvosi Hetilap, Vol. 150, No. 37, 01.09.2009, p. 1744-1748.

Research output: Contribution to journalArticle

Kulcsár, Zsolt ; Marosfoi, Miklós ; Berentei, Zsolt ; Veres, Róbert ; Nyáry, István ; Szikora, István. / Szomszédos csigolyatörések elo′fordulása percutan vertebroplastica után. In: Orvosi Hetilap. 2009 ; Vol. 150, No. 37. pp. 1744-1748.
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abstract = "Introduction and aims: Percutaneous vertebroplasty (PVP) proved to be very effective in the treatment of pain caused by osteoporotic vertebral compression fractures. A certain proportion of patients, however, suffer a new fracture after treatment. our purpose was to analyze the frequency of new fractures, and to estimate the causative role of PVP in the treated population. Methods: The retrospective study reviewed all consecutive patients treated with PVP for osteoporotic compression fractures during a 5.5 years period. The study group comprised those patients, who suffered a new fracture during the follow up. The primary endpoint was the frequency of new fractures. The secondary endpoint was the occurrence of new fractures in a timeframe of 90 days after treatment that were adjacent to the previously treated segments. The causative role of PVP was estimated to be the highest in this subgroup. Results: Altogether 396 consecutive patients were treated with PVP for osteoporotic compression fractures. Mean age was 68+11 years, and 23{\%} of the population was male. The study group comprised 73 patients (18.4{\%}). In this subgroup the patients had an average of 3.8 vertebral fractures. After PVP, adjacent fractures were significantly more likely, than distal fractures. Altogether 44 patients (11{\%} of the entire population) suffered an adjacent fracture in 90 days after PVP. In this group there were significantly less male patients as compared to the entire population. Conclusions: After PVP almost every fifth patient is at risk for developing a new fracture, however, it is likely to be related to the vertebral augmentation in every tenth subject only. Female patients with severe osteoporosis are probably facing the highest risk for developing new fractures.",
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AU - Marosfoi, Miklós

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AU - Veres, Róbert

AU - Nyáry, István

AU - Szikora, István

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N2 - Introduction and aims: Percutaneous vertebroplasty (PVP) proved to be very effective in the treatment of pain caused by osteoporotic vertebral compression fractures. A certain proportion of patients, however, suffer a new fracture after treatment. our purpose was to analyze the frequency of new fractures, and to estimate the causative role of PVP in the treated population. Methods: The retrospective study reviewed all consecutive patients treated with PVP for osteoporotic compression fractures during a 5.5 years period. The study group comprised those patients, who suffered a new fracture during the follow up. The primary endpoint was the frequency of new fractures. The secondary endpoint was the occurrence of new fractures in a timeframe of 90 days after treatment that were adjacent to the previously treated segments. The causative role of PVP was estimated to be the highest in this subgroup. Results: Altogether 396 consecutive patients were treated with PVP for osteoporotic compression fractures. Mean age was 68+11 years, and 23% of the population was male. The study group comprised 73 patients (18.4%). In this subgroup the patients had an average of 3.8 vertebral fractures. After PVP, adjacent fractures were significantly more likely, than distal fractures. Altogether 44 patients (11% of the entire population) suffered an adjacent fracture in 90 days after PVP. In this group there were significantly less male patients as compared to the entire population. Conclusions: After PVP almost every fifth patient is at risk for developing a new fracture, however, it is likely to be related to the vertebral augmentation in every tenth subject only. Female patients with severe osteoporosis are probably facing the highest risk for developing new fractures.

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