Szabad DNS-alapú vastagbéldaganat-szurés perifériás vérbol: a metilált szeptin-9 génmarker lehetoségei

Translated title of the contribution: Free circulating DNA based colorectal cancer screening from peripheral blood: The possibility of the methylated septin 9 gene marker

Kinga Tóth, Orsolya Galamb, Sándor Spisák, Barnabás Wichmann, Ferenc Sipos, Katalin Leiszter, Jeannette Molnár, Béla Molnár, Zsolt Tulassay

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

DNA methylation acts in early tumorigenesis. Its detection is possible either from tissue, stool or peripheral blood. Septin 9 is a sensitive methylation marker, which has been studied in several cancers such as breast and ovarian tumors and in neurological or hematological diseases. Septin proteins have an important role from cytoskeleton organisation to development of embryonal pattern. Nowadays intensive researches are going on about the relation between the septin 9 gene hypermethylation and colorectal cancer development.

Translated title of the contributionFree circulating DNA based colorectal cancer screening from peripheral blood: The possibility of the methylated septin 9 gene marker
Original languageHungarian
Pages (from-to)969-977
Number of pages9
JournalOrvosi hetilap
Volume150
Issue number21
DOIs
Publication statusPublished - May 1 2009

ASJC Scopus subject areas

  • Medicine(all)

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