Four spatial points that define enzyme families

Gábor Iván, Zoltán Szabadka, Rafael Ördög, Vince Grolmusz, Gábor Náray-Szabó

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8 Citations (Scopus)

Abstract

The catalytic properties of enzymes, containing the Asp-His-Ser triads are deeply investigated for a long time. Serine endopeptidases, cutinases, acetylcholinesterases, cellulases, among other enzymes, contain these triads. We found that solely the geometric properties of just four points in the spatial structure of these enzymes are characteristic to their family (Fig. 3).

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalBiochemical and biophysical research communications
Volume383
Issue number4
DOIs
Publication statusPublished - Jun 12 2009

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Keywords

  • Catalytic triad
  • Data mining
  • Protein Data Bank

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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