Four facets of a single brain: Behaviour, cerebral blood flow/metabolism, neuronal activity and neurotransmitter dynamics

S. Kéri, Balázs Gulyás

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural measures, (2) brain activation as reflected by blood flow and metabolic changes, (3) electrical activity of cells and cell-populations, and (4) neurotransmitter dynamics (release, receptor binding and reuptake). Using imaging techniques, we must take into consideration that even during the simplest task all of these processes operate in a closely interacting manner. Therefore, before drawing final conclusions about brain functions on the basis of a single aspect of these mechanisms, we must clarify the exact relationship among them. In this paper, we address this issue in order to draw attention to a number of uncertainties and controversies in the relationship of the four facets of brain functions.

Original languageEnglish
Pages (from-to)1097-1106
Number of pages10
JournalNeuroReport
Volume14
Issue number8
DOIs
Publication statusPublished - Jun 11 2003

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Cerebrovascular Circulation
Neurotransmitter Agents
Brain
Phrenology
Functional Neuroimaging
Uncertainty
Population

Keywords

  • Cerebral blood flow
  • Functional neuroimaging
  • Neurotransmitter
  • Positron emission tomography
  • Visual perception
  • Working memory

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Four facets of a single brain : Behaviour, cerebral blood flow/metabolism, neuronal activity and neurotransmitter dynamics. / Kéri, S.; Gulyás, Balázs.

In: NeuroReport, Vol. 14, No. 8, 11.06.2003, p. 1097-1106.

Research output: Contribution to journalArticle

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