Multipartikuláris gyógyszerhordozó rendszer formulálása tablettába préselt pelletek alkalmazásával

Translated title of the contribution: Formulation of multiparticular drug delivery systems by compressing pellets into tablets

Csobán Zsombor, Kállai Nikolett, Polgár Ádám, I. Antal

Research output: Contribution to journalArticle

Abstract

The use of multiparticulate drug delivery systems can contribute to more efficient and safe therapy while stability and incompatibility problems can be avoided as well. The aim of the present work was to review the possible ways of production of pellets containing multiparticulate units and studying the most important factors influencing the product quality attributes after tablet compression. The relationship between the formulation variables (compression pressures, different amounts of tableting excipients) and the dissolution profile of the gastroresistant coated beads were investigated.

Original languageHungarian
Pages (from-to)134-142
Number of pages9
JournalActa Pharmaceutica Hungarica
Volume83
Issue number4
Publication statusPublished - 2013

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Excipients
Drug Delivery Systems
Tablets
Pressure
Therapeutics

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Multipartikuláris gyógyszerhordozó rendszer formulálása tablettába préselt pelletek alkalmazásával. / Zsombor, Csobán; Nikolett, Kállai; Ádám, Polgár; Antal, I.

In: Acta Pharmaceutica Hungarica, Vol. 83, No. 4, 2013, p. 134-142.

Research output: Contribution to journalArticle

Zsombor, Csobán ; Nikolett, Kállai ; Ádám, Polgár ; Antal, I. / Multipartikuláris gyógyszerhordozó rendszer formulálása tablettába préselt pelletek alkalmazásával. In: Acta Pharmaceutica Hungarica. 2013 ; Vol. 83, No. 4. pp. 134-142.
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