Formulation of diazepam containing rectal suppositories and experiences of their biopharmaceutical study

G. Regdon, I. Bacskay, M. Kata, B. Selmeczi, M. Szikszay, A. Santa, G. S. Balint

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5 Citations (Scopus)

Abstract

Methodology and the results of the in vitro membrane diffusion and in vivo bioavailability studies are presented. The results confirm a correlation between in vitro and in vivo findings. Hydrophilic macrogol-mixture with great molecular mass can be recommended as the optimal vehicle for formulation of diazepam suppositories.

Original languageEnglish
Pages (from-to)346-349
Number of pages4
JournalPharmazie
Volume49
Issue number5
Publication statusPublished - Jan 1 1994

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ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Regdon, G., Bacskay, I., Kata, M., Selmeczi, B., Szikszay, M., Santa, A., & Balint, G. S. (1994). Formulation of diazepam containing rectal suppositories and experiences of their biopharmaceutical study. Pharmazie, 49(5), 346-349.