Formation, photophysics, and photochemistry of anionic lanthanide(III) mono- And bisporphyrins

Muhammad Imran, Melitta P. Kiss, Zsolt Valicsek, O. Horváth

Research output: Contribution to journalArticle

Abstract

Since water-soluble porphyrin complexes of lanthanides(III) have proved to be promising for medical applications (e.g., luminescence imaging, photodynamic therapy, and theranostics), the investigation of the formation, photophysical, and photochemical properties of such coordination compounds provides useful pieces of information for their potential usage. Steady-state and time-resolved fluorometry, UV–Vis absorption spectroscopy, and continuous-wave photolysis were utilized for this purpose. 5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrin formed mono- and bisporphyrin complexes with samarium(III), europium(III), and gadolinium(III) as representatives in the middle of the lanthanide series. The special photoinduced behavior of these compounds was mostly determined by the position of the metal center, which was located out of the ligand plane, thus distorting it. Besides, the photochemical and, especially, photophysical features of the corresponding mono- and bisporphyrin complexes were similar because, in the latter species, two monoporphyrins were connected by a weak metal bridge between the peripheral sulfonato substituents (tail-to-tail dimerization). The formation of these coordination compounds and the transformation reactions between the mono- and bisporphyrins were rather slow in the dark at room temperature. These processes were accelerated by visible irradiation. However, dissociation and, especially, redox degradation were the main photoreactions in these systems, although with low quantum yields. Additionally, depending on the excitation wavelength, new types of photoproducts were also detected.

Original languageEnglish
Article number1309
JournalMolecules
Volume24
Issue number7
DOIs
Publication statusPublished - Apr 3 2019

Fingerprint

Photochemistry
Lanthanoid Series Elements
Photochemical reactions
porphyrins
photochemical reactions
Metals
Samarium
Europium
Fluorometry
Photodynamic therapy
Dimerization
Photolysis
samarium
Porphyrins
Photochemotherapy
Gadolinium
Medical applications
Quantum yield
gadolinium
europium

Keywords

  • Charge separation
  • Europium
  • Fluorescence
  • Gadolinium
  • Lanthanide(III) ions
  • Ligand-to-metal-charge transfer
  • Out-of-plane metalloporphyrins
  • Photolysis
  • Samarium
  • Tail-to-tail oligomerization

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Formation, photophysics, and photochemistry of anionic lanthanide(III) mono- And bisporphyrins. / Imran, Muhammad; Kiss, Melitta P.; Valicsek, Zsolt; Horváth, O.

In: Molecules, Vol. 24, No. 7, 1309, 03.04.2019.

Research output: Contribution to journalArticle

Imran, Muhammad ; Kiss, Melitta P. ; Valicsek, Zsolt ; Horváth, O. / Formation, photophysics, and photochemistry of anionic lanthanide(III) mono- And bisporphyrins. In: Molecules. 2019 ; Vol. 24, No. 7.
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