Formation of mouse erythrocyte rosettes by human lymphocytes. A B cell marker

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Abstract

26.5 ± 8.6% of human peripheral lymphocytes form rosettes with mouse erythrocytes. There is a significant correlation between the numbers of mouse erythrocyte rosette forming (MERF) lymphocytes and immunoglobulin bearing cells. By density gradient centrifugation the MERF cells can be separated from the other lymphocytes. Studies on the isolated MERF cells indicate that every MERF lymphocyte is an Ig bearing cell, but they do not possess sheep erythrocyte binding receptors and cannot be stimulated with phytohaemagglutinin. Accordingly, the MERF lymphocytes are regarded as B cells.

Original languageEnglish
Pages (from-to)382-384
Number of pages3
JournalClinical and Experimental Immunology
Volume23
Issue number2
Publication statusPublished - 1976

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B-Lymphocytes
Erythrocytes
Lymphocytes
Erythrocyte Count
Density Gradient Centrifugation
Phytohemagglutinins
Immunoglobulins
Sheep

ASJC Scopus subject areas

  • Immunology

Cite this

Formation of mouse erythrocyte rosettes by human lymphocytes. A B cell marker. / Dobozy, A.; Husz, S.; Hunyadi, J.; Simon, N.

In: Clinical and Experimental Immunology, Vol. 23, No. 2, 1976, p. 382-384.

Research output: Contribution to journalArticle

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