Formation of formaldehyde from S-adenosyl-L[methyl-3H]methionme during enzymic transmethylation of histamine

Z. Huszti, E. Tyihák

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

The experiments described here show that radiolabelled formaldemethone is formed from the radiolabelled methyl group of S-adenosyl-L-methionine in the course of the enzymic conversion of histamine to Nτ-methylhistamine in the presence of dimedone suggesting that the formation of HCHO is probably linked to the enzymic transmethylation of histamine.

Original languageEnglish
Pages (from-to)362-366
Number of pages5
JournalFEBS Letters
Volume209
Issue number2
DOIs
Publication statusPublished - Dec 15 1986

Fingerprint

Histamine
Formaldehyde
S-Adenosylmethionine
Experiments
N-methylhistamine
dimedone
formaldemethone

Keywords

  • Enzymic transmethylation Histamine-N-itmethyltransferase
  • Formaldehyde
  • Histamine S-Adenosyl-L-methionine
  • TLC

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Formation of formaldehyde from S-adenosyl-L[methyl-3H]methionme during enzymic transmethylation of histamine. / Huszti, Z.; Tyihák, E.

In: FEBS Letters, Vol. 209, No. 2, 15.12.1986, p. 362-366.

Research output: Contribution to journalArticle

@article{b752c832deb9416d90fe671af64c117b,
title = "Formation of formaldehyde from S-adenosyl-L[methyl-3H]methionme during enzymic transmethylation of histamine",
abstract = "The experiments described here show that radiolabelled formaldemethone is formed from the radiolabelled methyl group of S-adenosyl-L-methionine in the course of the enzymic conversion of histamine to Nτ-methylhistamine in the presence of dimedone suggesting that the formation of HCHO is probably linked to the enzymic transmethylation of histamine.",
keywords = "Enzymic transmethylation Histamine-N-itmethyltransferase, Formaldehyde, Histamine S-Adenosyl-L-methionine, TLC",
author = "Z. Huszti and E. Tyih{\'a}k",
year = "1986",
month = "12",
day = "15",
doi = "10.1016/0014-5793(86)81143-7",
language = "English",
volume = "209",
pages = "362--366",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Formation of formaldehyde from S-adenosyl-L[methyl-3H]methionme during enzymic transmethylation of histamine

AU - Huszti, Z.

AU - Tyihák, E.

PY - 1986/12/15

Y1 - 1986/12/15

N2 - The experiments described here show that radiolabelled formaldemethone is formed from the radiolabelled methyl group of S-adenosyl-L-methionine in the course of the enzymic conversion of histamine to Nτ-methylhistamine in the presence of dimedone suggesting that the formation of HCHO is probably linked to the enzymic transmethylation of histamine.

AB - The experiments described here show that radiolabelled formaldemethone is formed from the radiolabelled methyl group of S-adenosyl-L-methionine in the course of the enzymic conversion of histamine to Nτ-methylhistamine in the presence of dimedone suggesting that the formation of HCHO is probably linked to the enzymic transmethylation of histamine.

KW - Enzymic transmethylation Histamine-N-itmethyltransferase

KW - Formaldehyde

KW - Histamine S-Adenosyl-L-methionine

KW - TLC

UR - http://www.scopus.com/inward/record.url?scp=0022887825&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022887825&partnerID=8YFLogxK

U2 - 10.1016/0014-5793(86)81143-7

DO - 10.1016/0014-5793(86)81143-7

M3 - Article

C2 - 3792555

AN - SCOPUS:0022887825

VL - 209

SP - 362

EP - 366

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 2

ER -