Formation of aromatic amidoximes with hydroxylamine using microreactor technology

Attila Vörös, Zoltán Baán, Péter Mizsey, Zoltán Finta

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11 Citations (Scopus)


In this contribution, the application of microreactor technology for amidoxime formation is demonstrated, with different aromatic nitriles reacted with a 50% solution of hydroxylamine (HA) under homogeneous conditions to reach full conversion. All reactions were executed in the presence of an excess of HA at an elevated temperature near to Tonset of HA, but in safe mode. Upscaling was performed with success by the adaptation of an increased volume microreactor and by numbering-up.

Original languageEnglish
Pages (from-to)1717-1726
Number of pages10
JournalOrganic Process Research and Development
Issue number11
Publication statusPublished - Nov 16 2012


ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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