In this contribution, the application of microreactor technology for amidoxime formation is demonstrated, with different aromatic nitriles reacted with a 50% solution of hydroxylamine (HA) under homogeneous conditions to reach full conversion. All reactions were executed in the presence of an excess of HA at an elevated temperature near to Tonset of HA, but in safe mode. Upscaling was performed with success by the adaptation of an increased volume microreactor and by numbering-up.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry