Formation and isolation of bovine serum albumin in particulate solid form

J. Tóth, Elisabeth Pallai-Varsányi, János Gyenis

Research output: Contribution to journalArticle

Abstract

The aim of this study was to investigate what kind of combination and conditions of the consecutive processing steps - precipitation, separation and drying - can be used for the production of protein powders with acceptable particle size and preserved conformation. For model material bovine serum albumin (BSA) was chosen, which was salted out from its buffered solutions by polyethylene glycol (PEG). Drying experiments were performed to obtain information how the composition of the protein/buffer/precipitant ternary system influence the recovery of the protein in dried, powder-like form. For this, intensive, well controlled heat and mass-transfer have been carried out in a so called 'short time' drying by mechanically spouted bed (MSB) dryer with inert particles.

Original languageEnglish
Article numberC-5
Pages (from-to)575-580
Number of pages6
JournalVDI Berichte
Issue number1901 II
Publication statusPublished - 2005

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Drying
Proteins
Powders
Ternary systems
Polyethylene glycols
Conformations
Mass transfer
Particle size
Heat transfer
Recovery
Processing
Chemical analysis
Experiments

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Tóth, J., Pallai-Varsányi, E., & Gyenis, J. (2005). Formation and isolation of bovine serum albumin in particulate solid form. VDI Berichte, (1901 II), 575-580. [C-5].

Formation and isolation of bovine serum albumin in particulate solid form. / Tóth, J.; Pallai-Varsányi, Elisabeth; Gyenis, János.

In: VDI Berichte, No. 1901 II, C-5, 2005, p. 575-580.

Research output: Contribution to journalArticle

Tóth, J, Pallai-Varsányi, E & Gyenis, J 2005, 'Formation and isolation of bovine serum albumin in particulate solid form', VDI Berichte, no. 1901 II, C-5, pp. 575-580.
Tóth J, Pallai-Varsányi E, Gyenis J. Formation and isolation of bovine serum albumin in particulate solid form. VDI Berichte. 2005;(1901 II):575-580. C-5.
Tóth, J. ; Pallai-Varsányi, Elisabeth ; Gyenis, János. / Formation and isolation of bovine serum albumin in particulate solid form. In: VDI Berichte. 2005 ; No. 1901 II. pp. 575-580.
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