Forced-Flow Layer Chromatography

Research output: Book/ReportBook

4 Citations (Scopus)

Abstract

Forced-Flow Layer Chromatography takes a close look at the specifics of forced-flow layer chromatography techniques, from their evolution to the nuances of using these techniques in a variety of applications where traditional thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC) are not as effective. This book presents a number of variations of TLC techniques, with special emphasis on the overpressured-layer chromatography (OPLC) technique and newer developments such as the BioArena System for biomedical analysis. The versatility of these forced-flow techniques opens up new avenues for the analysis of a large number of samples for high-throughput screening and for the analysis of very complex matrices, while the development of BioArena extends the use of these techniques to challenging new areas of bioanalysis. Details a variety of forced-flow techniques, explaining how they markedly reduce developing time and result in less lateral diffusion and more compact spots. Emphasizes the benefits of OPLC separation techniques, a method pioneered by the authors nearly forty years ago. Discusses new developments, such as the BioArena system used to facilitate detection, isolation, and identification of new antimicrobials, antineoplastics, biopesticides, and other biologically active substances.

Original languageEnglish
PublisherElsevier Inc.
Number of pages510
ISBN (Print)9780124201613
Publication statusPublished - Dec 2 2015

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Chromatography
Thin layer chromatography
Biological Control Agents
Antineoplastic Agents
Screening
Throughput

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Forced-Flow Layer Chromatography. / Tyihák, E.

Elsevier Inc., 2015. 510 p.

Research output: Book/ReportBook

Tyihák E. Forced-Flow Layer Chromatography. Elsevier Inc., 2015. 510 p.
Tyihák, E. / Forced-Flow Layer Chromatography. Elsevier Inc., 2015. 510 p.
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