Force barriers for membrane tube formation

Gerbrand Koster, Angelo Cacciuto, I. Derényi, Daan Frenkel, Marileen Dogterom

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

We used optical tweezers to measure the force-extension curve for the formation of tubes from giant vesicles. We show that a significant force barrier exists for the formation of tubes, which increases linearly with the radius of the area on which the pulling force is exerted. The tubes form through a first-order transition with accompanying hysteresis. We confirm these results with Monte Carlo simulations and theoretical calculations. Whether membrane tubes can be formed in, for example, biological cells, thus depends on the details of how forces are applied.

Original languageEnglish
Article number068101
JournalPhysical Review Letters
Volume94
Issue number6
DOIs
Publication statusPublished - Feb 18 2005

Fingerprint

Optical Tweezers
tubes
membranes
Membranes
pulling
hysteresis
radii
curves
simulation

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Medicine(all)

Cite this

Koster, G., Cacciuto, A., Derényi, I., Frenkel, D., & Dogterom, M. (2005). Force barriers for membrane tube formation. Physical Review Letters, 94(6), [068101]. https://doi.org/10.1103/PhysRevLett.94.068101

Force barriers for membrane tube formation. / Koster, Gerbrand; Cacciuto, Angelo; Derényi, I.; Frenkel, Daan; Dogterom, Marileen.

In: Physical Review Letters, Vol. 94, No. 6, 068101, 18.02.2005.

Research output: Contribution to journalArticle

Koster, G, Cacciuto, A, Derényi, I, Frenkel, D & Dogterom, M 2005, 'Force barriers for membrane tube formation', Physical Review Letters, vol. 94, no. 6, 068101. https://doi.org/10.1103/PhysRevLett.94.068101
Koster, Gerbrand ; Cacciuto, Angelo ; Derényi, I. ; Frenkel, Daan ; Dogterom, Marileen. / Force barriers for membrane tube formation. In: Physical Review Letters. 2005 ; Vol. 94, No. 6.
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