Food allergy in patients with respiratory allergic symptoms

Z. F. Kiss, E. Kadocsa, S. Husz, K. Jármay, G. Lencse, T. Wittmann, J. Lonovics

Research output: Contribution to journalArticle

Abstract

The chronic respiratory allergic symptoms are often associated with skin lesions and abdominal complaints. Our aim was to clarify whether allergic mechanisms are involved in the pathogenesis of abdominal complaints in patients suffering from allergic respiratory symptoms. For this reason in 28 patients the skin tests with inhalative and nutritive allergens, the evaluation of allergen-specific IgG antibody levels by ELISA method were performed. Moreover the leukocyte migration inhibition test against the same allergens and histological examination of the stomach and the duodenum for mucosal mastocytes were undergone. The results of skin test was positive for inhalative allergens in 23/28 patients, and for the main foodstuffs in 18/27 patients. The food-specific IgG antibody level was increased against one or more antigens in 18/27 patients. The leukocyte migration inhibition test was positive against one or more main food products in 23/27 cases. Endoscopic examinations revealed that the number of mucosal mast cells was increased in 22/27 patients. Our results suggest that food antigens play an immunopathogenetic role in the development of abdominal symptoms in patients with respiratory allergic disease. Examination of the mucosal mast cells confirms the disturbance of the immunoregulatory mechanisms in the gastrointestinal tract.

Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalInternational Review of Allergology and Clinical Immunology
Volume7
Issue number2
Publication statusPublished - Jan 1 2001

Keywords

  • Food allergy
  • Food-specific IgG antibody
  • Leukocyte migration inhibition test
  • Mucosal mast cells
  • Skin prick test

ASJC Scopus subject areas

  • Immunology and Allergy

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