Following the goose liver development by means of cross-sectional digital imaging, liver histology and blood biochemical parameters

L. Locsmándi, G. Hegedüs, G. Andrássy-Baka, F. Bogenfürst, R. Romvári

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A follow-up study was performed to describe characteristic physiological alterations by means of computer tomography, direct chemical analysis and histology of the liver, and blood biochemical parameters during conventional force-feeding of Landes geese. 30 birds were exposed to an 18-day long force-feeding. Sampling was performed at the start and during force-feeding (7th, 11th, 14th, 18th days). Computer tomographic data were plotted in 3D histograms, effectively indicating the volumetric development and the fat deposition of the liver. Applying the so-called fat index, a saturation process was found for the hepatic fat content. Histological sections indicated the appearance of microvesicular fat forms in the hepatocyte cytoplasm, which first turned to a total fatty infiltration, later changing to a macrovesicular form with progressing inflammation; membrane damage was not visualized. In blood metabolites triglyceride, total and HDL cholesterol and uric acid increased measurably, while creatinine concentration decreased. Alanine aminotransferase, aspartate aminotransferase activities increased strongly, while that of lactate dehydrogenase only slightly. Based on the results of macroscopic and microscopic imaging techniques and blood biochemical parameters, a comprehensive follow-up study was performed, elucidating still unknown processes during force-feeding of geese.

Original languageEnglish
Pages (from-to)35-48
Number of pages14
JournalActa biologica Hungarica
Volume58
Issue number1
DOIs
Publication statusPublished - Mar 1 2007

Keywords

  • Computerized tomography
  • Goose liver
  • Liver histology
  • Serum biochemical parameters

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

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