Fluorination of some highly functionalized cycloalkanes: Chemoselectivity and substrate dependence

Attila Márió Remete, Melinda Nonn, Santos Fustero, Matti Haukka, F. Fülöp, L. Kiss

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A study exploring the chemical behavior of some dihydroxylated β-amino ester stereo- and regioisomers, derived from unsaturated cyclic β-amino acids is described. The nucleophilic fluorinations involving hydroxy-fluorine exchange of some highly functionalized alicyclic diol derivatives have been carried out in view of selective fluorination, investigating substrate dependence, neighboring group assistance and chemodifferentiation.

Original languageEnglish
Pages (from-to)2364-2371
Number of pages8
JournalBeilstein Journal of Organic Chemistry
Volume13
DOIs
Publication statusPublished - Nov 6 2017

Fingerprint

Cycloparaffins
Fluorination
Cyclic Amino Acids
Stereoisomerism
Fluorine
Substrates
Ion exchange
Esters
Derivatives

Keywords

  • Amino acids
  • Chemoselectivity
  • Fluorine
  • Functionalization
  • Stereoisomers

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Fluorination of some highly functionalized cycloalkanes : Chemoselectivity and substrate dependence. / Remete, Attila Márió; Nonn, Melinda; Fustero, Santos; Haukka, Matti; Fülöp, F.; Kiss, L.

In: Beilstein Journal of Organic Chemistry, Vol. 13, 06.11.2017, p. 2364-2371.

Research output: Contribution to journalArticle

Remete, Attila Márió ; Nonn, Melinda ; Fustero, Santos ; Haukka, Matti ; Fülöp, F. ; Kiss, L. / Fluorination of some highly functionalized cycloalkanes : Chemoselectivity and substrate dependence. In: Beilstein Journal of Organic Chemistry. 2017 ; Vol. 13. pp. 2364-2371.
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