Fluorescent silica nanoparticles

Heike Mader, Xiaohua Li, Sayed Saleh, Martin Link, Peter Kele, Otto S. Wolfbeis

Research output: Contribution to journalArticle

45 Citations (Scopus)


We report on the preparation of fluorescent silica nanoparticles (NPs). They have been prepared by (a) modification of the NPs by amino groups and subsequent introduction of amino-reactive fluorophores of various color and (b) by modification of the NPs by either azido groups or alkyne groups and subsequent conjugation to fluorophores by so-called click chemistry, which is a novel approach toward modifying silica NPs. The new NPs were characterized in terms of size and spectral properties.

Original languageEnglish
Pages (from-to)218-223
Number of pages6
JournalAnnals of the New York Academy of Sciences
Publication statusPublished - May 2008



  • Click chemistry
  • Click reaction
  • Fluorescence
  • Silica nanoparticles

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

Mader, H., Li, X., Saleh, S., Link, M., Kele, P., & Wolfbeis, O. S. (2008). Fluorescent silica nanoparticles. Annals of the New York Academy of Sciences, 1130, 218-223. https://doi.org/10.1196/annals.1430.053