Fluorescent nanoparticles based on chitosan

M. Bodnar, T. Minko, J. F. Hartmann, J. Borbely

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

The present investigation reports the formation and characterization of novel biocompatible chitosan nanoparticles based conjugated with fluorescent dye for biomedical applications. The solubility and size of these nanoparticles in the dried and swollen states will be described and discussed. The correlation of size of nanoparticles, pH of the solutions, ratio of cross-linking, and the dye-content of nanosystems have been studied. It was found, that biocompatible fluorescent chitosan nanosystems have been successfully prepared. The size and the size distributions of the nanosystems depend on the pH, but at a given pH, it was independent of the ratio of cross-linking. The diameter of individual dried particles varied in the range of 100-300 nm, and the average hydrodynamic diameters were in the range of 270-370 nm depending on the pH. The biocompatible fluorescent chitosan nanoparticles in aqueous media, might be useful for various in vitro experiments related to biomedical applications.

Original languageEnglish
Title of host publication2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Pages279-282
Number of pages4
Publication statusPublished - Aug 23 2007
Event2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007 - Santa Clara, CA, United States
Duration: May 20 2007May 24 2007

Publication series

Name2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Volume2

Other

Other2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007
CountryUnited States
CitySanta Clara, CA
Period5/20/075/24/07

    Fingerprint

Keywords

  • Chitosan
  • Fluorescent
  • Nanoparticles

ASJC Scopus subject areas

  • Mechanical Engineering

Cite this

Bodnar, M., Minko, T., Hartmann, J. F., & Borbely, J. (2007). Fluorescent nanoparticles based on chitosan. In 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings (pp. 279-282). (2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings; Vol. 2).