Mellékvesekéreg-daganatok dezoxiribonukleinsav-tartalmának átáramoltatásos citometriás vizsgálata.

Translated title of the contribution: Flow-cytometric study of the DNA content in adrenal cortex tumors

M. Tóth, G. Molnár, Z. Schaff, K. Rácz, R. Kiss, L. Fütö, I. Varga, E. Gláz, K. Lapis

Research output: Contribution to journalArticle

Abstract

Flow cytometric deoxyribonucleic acid measurements were performed on 26 adrenocortical tumours and 9 non-tumours adrenals. All but one tumours were classified both histologically and clinically as benign, however, two thirds of them had abnormal deoxyribonucleic acid stemlines. Proliferative indices of adenomatous tissues were significantly higher than those of non-tumorous adrenals (p <0.01). When compared to tumors smaller than 5 cm in size, tumours larger than 5 cm displayed significantly higher proliferative indices (p <0.01). Thus, flow cytometry appears to have only a limited value in distinguishing between benign and malignant adrenocortical tumours, but it may provide additional information about the prognosis of these tumours.

Original languageHungarian
Pages (from-to)1411-1415
Number of pages5
JournalOrvosi Hetilap
Volume134
Issue number26
Publication statusPublished - Jun 27 1993

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Adrenal Cortex
DNA
Neoplasms
Flow Cytometry

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mellékvesekéreg-daganatok dezoxiribonukleinsav-tartalmának átáramoltatásos citometriás vizsgálata. / Tóth, M.; Molnár, G.; Schaff, Z.; Rácz, K.; Kiss, R.; Fütö, L.; Varga, I.; Gláz, E.; Lapis, K.

In: Orvosi Hetilap, Vol. 134, No. 26, 27.06.1993, p. 1411-1415.

Research output: Contribution to journalArticle

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abstract = "Flow cytometric deoxyribonucleic acid measurements were performed on 26 adrenocortical tumours and 9 non-tumours adrenals. All but one tumours were classified both histologically and clinically as benign, however, two thirds of them had abnormal deoxyribonucleic acid stemlines. Proliferative indices of adenomatous tissues were significantly higher than those of non-tumorous adrenals (p <0.01). When compared to tumors smaller than 5 cm in size, tumours larger than 5 cm displayed significantly higher proliferative indices (p <0.01). Thus, flow cytometry appears to have only a limited value in distinguishing between benign and malignant adrenocortical tumours, but it may provide additional information about the prognosis of these tumours.",
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