Five-component equilibria of ring-chain tautomeric mixtures derived from 3-amino-1,2-propanediol and aromatic aldehydes

Lászlo Lázár, Attila G. Lakatos, Ferenc Fülöp, Gábor Bernáth, Frank G. Riddell

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In the reactions of 3-amino-1,2-propanediol with aromatic aldehydes, five-component ring-chain tautomeric mixtures were formed, involving oxazolidine and oxazine C-2 epimers and the corresponding Schiff base. These multicomponent tautomeric equilibria could be described by the equation log K = ρσ + log K0, used earlier for the two- and three-component equilibria relating to only oxazine or oxazolidine ring.

Original languageEnglish
Pages (from-to)1081-1088
Number of pages8
Issue number3
Publication statusPublished - Jan 20 1997


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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