First record of autochthonous canine leishmaniasis in Hungary

Balázs Tánczos, Nándor Balogh, László Király, Imre Biksi, L. Szeredi, Monika Gyurkovsky, Aldo Scalone, Eleonora Fiorentino, Marina Gramiccia, R. Farkas

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Hungary is traditionally regarded as a leishmaniasis-free country, and human or canine cases diagnosed locally have been recorded as imported. However, recent entomological surveys have verified the presence in Hungary of Phlebotomus neglectus and Phlebotomus perfiliewi perfiliewi, which have been incriminated as competent vectors of Leishmania infantum elsewhere in Europe. Following the occurrence in October 2007 of an undisputable clinical case of L. infantum canine leishmaniasis (CanL) in a 4-year-old female pug in a kennel of 20 dogs in Tolna province, an investigation was performed to assess the infection status in that canine population and to search for putative phlebotomine vectors. Another female pug became sick during the study period (May-November 2008) and L. infantum was confirmed as the causative agent. The other animals appeared clinically healthy; however, 4 additional dogs were found positive by indirect fluorescent antibody test (2 dogs), or by buffy-coat PCR (1 dog), or by both methods (1 dog). Hence the overall Leishmania infection prevalence in the kennel was 30% (6/20). All dogs were born in the same place and had been always kept outdoors. They had neither been abroad nor received a blood transfusion. No sand flies were collected with CDC Standard Miniature Light traps, Mosquito Magnet® X (MMX) dry ice-baited traps, or sticky traps placed either in or around the kennel and at nearby chicken yards during July and August of 2008 and 2009. Considering the dogs' historical background and the failure to trap any sand fly vectors in the kennel area, the origin of CanL in this site remains unexplained.

Original languageEnglish
Pages (from-to)588-594
Number of pages7
JournalVector-Borne and Zoonotic Diseases
Volume12
Issue number7
DOIs
Publication statusPublished - Jul 1 2012

Fingerprint

Leishmaniasis
Hungary
Canidae
Dogs
Leishmania infantum
Phlebotomus
Psychodidae
Dry Ice
Magnets
Leishmania
Centers for Disease Control and Prevention (U.S.)
Infection
Culicidae
Blood Transfusion
Chickens
Light
Polymerase Chain Reaction
Antibodies
Population

Keywords

  • Dog
  • Hungary
  • Indirect fluorescent antibody test
  • Kinetoplast DNA PCR
  • Leishmania infantum
  • Leishmaniasis-Ribosomal DNA nested PCR
  • Sand fly

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology
  • Virology

Cite this

First record of autochthonous canine leishmaniasis in Hungary. / Tánczos, Balázs; Balogh, Nándor; Király, László; Biksi, Imre; Szeredi, L.; Gyurkovsky, Monika; Scalone, Aldo; Fiorentino, Eleonora; Gramiccia, Marina; Farkas, R.

In: Vector-Borne and Zoonotic Diseases, Vol. 12, No. 7, 01.07.2012, p. 588-594.

Research output: Contribution to journalArticle

Tánczos, B, Balogh, N, Király, L, Biksi, I, Szeredi, L, Gyurkovsky, M, Scalone, A, Fiorentino, E, Gramiccia, M & Farkas, R 2012, 'First record of autochthonous canine leishmaniasis in Hungary', Vector-Borne and Zoonotic Diseases, vol. 12, no. 7, pp. 588-594. https://doi.org/10.1089/vbz.2011.0906
Tánczos, Balázs ; Balogh, Nándor ; Király, László ; Biksi, Imre ; Szeredi, L. ; Gyurkovsky, Monika ; Scalone, Aldo ; Fiorentino, Eleonora ; Gramiccia, Marina ; Farkas, R. / First record of autochthonous canine leishmaniasis in Hungary. In: Vector-Borne and Zoonotic Diseases. 2012 ; Vol. 12, No. 7. pp. 588-594.
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