First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead

Johannes Sperzel, Wilfried Dänschel, Klaus Jürgen Gutleben, Wolfgang Kranig, Peter Mortensen, Derek Connelly, Hans Joachim Trappe, Karlheinz Seidl, G. Duray, Burkert Pieske, Jochem Stockinger, Giuseppe Boriani, Werner Jung, Richard Schilling, Linda Saberi, Benoit Hallier, Marcus Simon, Christopher A. Rinaldi

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Aims Cardiac resynchronization therapy (CRT) is sometimes complicated by elevated pacing thresholds and phrenic nerve stimulation (PNS), both of which may require that the coronary sinus lead be repositioned. The purpose of this study was to evaluate the performance of a novel quadripolar electrode lead and cardiac resynchronization therapy-defibrillator (CRT-D) device that enables electrical repositioning, potentially obviating a lead reposition procedure. Methods and resultsPatients indicated for CRT were enrolled and received a quadripolar electrode lead and CRT-D device (Quartet®model 1458Q and Promote Q®; St Jude Medical, Sylmar, CA, USA). Electrical data, and the presence of PNS during pacing from each left ventricular (LV) configuration, were documented at pre-hospital discharge and at 1 month. Seventy-five patients were enrolled and 71 were successfully implanted with a Quartet®lead. Electrical measurements were stable over the follow-up period. Ninety-seven per cent (64 of 66) of patients had one or more programmable configurations with a threshold

Original languageEnglish
Pages (from-to)365-372
Number of pages8
JournalEuropace
Volume14
Issue number3
DOIs
Publication statusPublished - Mar 2012

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Cardiac Resynchronization Therapy Devices
Cardiac Resynchronization Therapy
Phrenic Nerve
Electrodes
Defibrillators
Coronary Sinus
Lead

Keywords

  • Cardiac resynchronization therapy
  • Left ventricular pacing
  • LV lead complications
  • Phrenic nerve stimulation
  • Quadripolar lead

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Sperzel, J., Dänschel, W., Gutleben, K. J., Kranig, W., Mortensen, P., Connelly, D., ... Rinaldi, C. A. (2012). First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead. Europace, 14(3), 365-372. https://doi.org/10.1093/europace/eur322

First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead. / Sperzel, Johannes; Dänschel, Wilfried; Gutleben, Klaus Jürgen; Kranig, Wolfgang; Mortensen, Peter; Connelly, Derek; Trappe, Hans Joachim; Seidl, Karlheinz; Duray, G.; Pieske, Burkert; Stockinger, Jochem; Boriani, Giuseppe; Jung, Werner; Schilling, Richard; Saberi, Linda; Hallier, Benoit; Simon, Marcus; Rinaldi, Christopher A.

In: Europace, Vol. 14, No. 3, 03.2012, p. 365-372.

Research output: Contribution to journalArticle

Sperzel, J, Dänschel, W, Gutleben, KJ, Kranig, W, Mortensen, P, Connelly, D, Trappe, HJ, Seidl, K, Duray, G, Pieske, B, Stockinger, J, Boriani, G, Jung, W, Schilling, R, Saberi, L, Hallier, B, Simon, M & Rinaldi, CA 2012, 'First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead', Europace, vol. 14, no. 3, pp. 365-372. https://doi.org/10.1093/europace/eur322
Sperzel J, Dänschel W, Gutleben KJ, Kranig W, Mortensen P, Connelly D et al. First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead. Europace. 2012 Mar;14(3):365-372. https://doi.org/10.1093/europace/eur322
Sperzel, Johannes ; Dänschel, Wilfried ; Gutleben, Klaus Jürgen ; Kranig, Wolfgang ; Mortensen, Peter ; Connelly, Derek ; Trappe, Hans Joachim ; Seidl, Karlheinz ; Duray, G. ; Pieske, Burkert ; Stockinger, Jochem ; Boriani, Giuseppe ; Jung, Werner ; Schilling, Richard ; Saberi, Linda ; Hallier, Benoit ; Simon, Marcus ; Rinaldi, Christopher A. / First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead. In: Europace. 2012 ; Vol. 14, No. 3. pp. 365-372.
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