First molecular identification of 'candidatus mycoplasma haemominutum' from a cat with fatal haemolytic anaemia in Hungary

S. Hornok, Marina L. Meli, Eniko Gönczi, Éva Ignits, Barbara Willi, Hans Lutz, Regina Hofmann-Lehmann

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Although haemobartonellosis was previously reported in Hungary, until now the diagnosis (based on morphological identification in blood smears) has only been suggestive of the occurrence of the large species, recently reclassified as Mycoplasma haemofelis. However, in July 2007 a cat was presented at a small animal clinic with severe haemolytic anaemia, icterus and haemoglobinuria. While biochemical parameters were within the reference range, the cat had leukocytosis and rapidly decreasing haematocrit values, and eventually died 7 days after the sudden onset of aggravating clinical signs. From blood samples of the cat 'Candidatus Mycoplasma haemominutum' was identified by molecular methods, according to its 100% 16S rRNA gene sequence homology with two Swiss isolates and one isolate from the UK. The rapid termination of the disease and the high pathogenicity of the causative agent observed in this case are unusual, taking into account that PCR results were negative for immunosuppressive viruses. This is the first record of this feline haemoplasma species in Hungary.

Original languageEnglish
Pages (from-to)441-450
Number of pages10
JournalActa Veterinaria Hungarica
Volume56
Issue number4
DOIs
Publication statusPublished - Dec 2008

Fingerprint

Mycoplasma haemominutum
hemolytic anemia
Hungary
Mycoplasma
Hemolytic Anemia
Cats
cats
Anaplasmataceae Infections
Hemoglobinuria
Felidae
Leukocytosis
Mycoplasma haemofelis
hemoglobinuria
Immunosuppressive Agents
Sequence Homology
Jaundice
rRNA Genes
Hematocrit
immunosuppressive agents
Virulence

Keywords

  • Candidatus mycoplasma haemominutum
  • Feline infectious anaemia
  • Real-time PCR

ASJC Scopus subject areas

  • veterinary(all)

Cite this

First molecular identification of 'candidatus mycoplasma haemominutum' from a cat with fatal haemolytic anaemia in Hungary. / Hornok, S.; Meli, Marina L.; Gönczi, Eniko; Ignits, Éva; Willi, Barbara; Lutz, Hans; Hofmann-Lehmann, Regina.

In: Acta Veterinaria Hungarica, Vol. 56, No. 4, 12.2008, p. 441-450.

Research output: Contribution to journalArticle

Hornok, S. ; Meli, Marina L. ; Gönczi, Eniko ; Ignits, Éva ; Willi, Barbara ; Lutz, Hans ; Hofmann-Lehmann, Regina. / First molecular identification of 'candidatus mycoplasma haemominutum' from a cat with fatal haemolytic anaemia in Hungary. In: Acta Veterinaria Hungarica. 2008 ; Vol. 56, No. 4. pp. 441-450.
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