First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient

Ratna Mohd Tap, Lee Sue Ho Betty, Nur Yasmin Ramli, Jeyanthi Suppiah, Rohaidah Hashim, Parameswari Sabaratnam, Stephanie Jane Ginsapu, Annabel Gowbei, Mohd Fuat Abd Razak, Matthias Sipiczki, Norazah Ahmad

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Abstract

Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C. wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name as UZ1679/14, in which the identification was confirmed by a polymerase chain reaction-sequencing of the internal transcribed spacer (ITS) and large subunit (LSU) regions of the rRNA gene. Antifungal susceptibility pattern showed that the isolate was sensitive to anidulafungin, caspofungin, fluconazole and voriconazole. The patient clinically improved after the antifungal treatment with caspofungin.

Original languageEnglish
Pages (from-to)734-741
Number of pages8
JournalMycoses
Volume59
Issue number11
DOIs
Publication statusPublished - Nov 1 2016

Keywords

  • Candida wangnamkhiaoensis
  • Hypopichia clade
  • fungaemia
  • immunocompromised patient

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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  • Cite this

    Tap, R. M., Ho Betty, L. S., Ramli, N. Y., Suppiah, J., Hashim, R., Sabaratnam, P., Ginsapu, S. J., Gowbei, A., Razak, M. F. A., Sipiczki, M., & Ahmad, N. (2016). First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient. Mycoses, 59(11), 734-741. https://doi.org/10.1111/myc.12509