Humán metapneumovírus elso hazai kimutatása gyermekkori légúti fertozésbol

Translated title of the contribution: First detection of human metapneumovirus in a child with respiratory syndrome in Hungary

G. Reuter, Hajnalka Szabó, Gyöngyi Székely, K. Gyurkovits, György Szucs

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Introduction: Human metapneumovirus was identified in 2001 as a respiratory-tract pathogen that has been classified as a new genera in family Paramyxoviridae. Aims: Molecular detection of human metapneumovirus in Hungary. Materials and methods: Human metapneumovirus was identified in nasopharyngeal aspirate amplification of the viral fusion and nucleocapsid genes by reverse transcription-polymerase chain reaction followed by sequencing and phylogenetic analysis. Results: A 4 years-old girl with chronic respiratory syndrome chronically treated with anti-asthma drugs was admitted to hospital in November 2005 with acute respiratory syndrome and atelectasis. Nasopharyngeal aspirate was negative for common bacteria by culture and for influenza and coronavirus by reverse transcription-polymerase chain reaction. By contrast, specimen was positive by reverse transcription-polymerase chain reaction and was confirmed by sequencing both genes (nucleocapsid and fusion) of human metapneumovirus. Human metapneumovirus (HUN 05-L20) clustered into the subgroup B1 has the closest nucleotide similarity (98%) to JPS03-194 (AY530094) detected in Japan. Conclusions: Human metapneumovirus contributes as an etiological agent of acute lower and upper respiratory tract infection especially in winter season in children with bronchiolitis, pneumonia or episodes of asthma exacerbation in Hungary, too.

Original languageHungarian
Pages (from-to)2299-2302
Number of pages4
JournalOrvosi Hetilap
Volume147
Issue number48
Publication statusPublished - Dec 3 2006

Fingerprint

Metapneumovirus
Hungary
Reverse Transcription
Nucleocapsid
Gene Fusion
Polymerase Chain Reaction
Paramyxoviridae
Asthma
Coronavirus
Bronchiolitis
Pulmonary Atelectasis
Respiratory Tract Infections
Respiratory System
Human Influenza
Pneumonia
Japan
Nucleotides
Bacteria
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Humán metapneumovírus elso hazai kimutatása gyermekkori légúti fertozésbol. / Reuter, G.; Szabó, Hajnalka; Székely, Gyöngyi; Gyurkovits, K.; Szucs, György.

In: Orvosi Hetilap, Vol. 147, No. 48, 03.12.2006, p. 2299-2302.

Research output: Contribution to journalArticle

Reuter, G, Szabó, H, Székely, G, Gyurkovits, K & Szucs, G 2006, 'Humán metapneumovírus elso hazai kimutatása gyermekkori légúti fertozésbol', Orvosi Hetilap, vol. 147, no. 48, pp. 2299-2302.
Reuter, G. ; Szabó, Hajnalka ; Székely, Gyöngyi ; Gyurkovits, K. ; Szucs, György. / Humán metapneumovírus elso hazai kimutatása gyermekkori légúti fertozésbol. In: Orvosi Hetilap. 2006 ; Vol. 147, No. 48. pp. 2299-2302.
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