Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation

Haojie Mao, Liying Zhang, King H. Yang, Albert I. King, J. Pál, Ferenc Gallyas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Biomechanical responses of a rat brain in a new weight-drop model were investigated by comparing histological results against finite element model predictions. This graded axonal injury rat model differed from others because of its utilization of intact skull without global angular motion to confound data analyses. Results demonstrated that the maximum principal strain and the compressive strain along the impact direction best correlated the experimentally observed injury locations while the shear strain did not have positive correlation.

Original languageEnglish
Title of host publicationProceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages1061-1062
Number of pages2
EditionPART B
Publication statusPublished - 2009
Event10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States
Duration: Jun 25 2008Jun 29 2008

Other

Other10th ASME Summer Bioengineering Conference, SBC2008
CountryUnited States
CityMarco Island, FL
Period6/25/086/29/08

Fingerprint

Brain models
Finite Element Analysis
Biomechanics
Craniocerebral Trauma
Biomechanical Phenomena
Skull
Tissue
Finite element method
Rats
Wounds and Injuries
Brain
Shear strain
Weights and Measures

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Mao, H., Zhang, L., Yang, K. H., King, A. I., Pál, J., & Gallyas, F. (2009). Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008 (PART B ed., pp. 1061-1062)

Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation. / Mao, Haojie; Zhang, Liying; Yang, King H.; King, Albert I.; Pál, J.; Gallyas, Ferenc.

Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B. ed. 2009. p. 1061-1062.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mao, H, Zhang, L, Yang, KH, King, AI, Pál, J & Gallyas, F 2009, Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation. in Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B edn, pp. 1061-1062, 10th ASME Summer Bioengineering Conference, SBC2008, Marco Island, FL, United States, 6/25/08.
Mao H, Zhang L, Yang KH, King AI, Pál J, Gallyas F. Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation. In Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B ed. 2009. p. 1061-1062
Mao, Haojie ; Zhang, Liying ; Yang, King H. ; King, Albert I. ; Pál, J. ; Gallyas, Ferenc. / Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation. Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B. ed. 2009. pp. 1061-1062
@inproceedings{32d40210e5e149919b5d6f68bae3510c,
title = "Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation",
abstract = "Biomechanical responses of a rat brain in a new weight-drop model were investigated by comparing histological results against finite element model predictions. This graded axonal injury rat model differed from others because of its utilization of intact skull without global angular motion to confound data analyses. Results demonstrated that the maximum principal strain and the compressive strain along the impact direction best correlated the experimentally observed injury locations while the shear strain did not have positive correlation.",
author = "Haojie Mao and Liying Zhang and Yang, {King H.} and King, {Albert I.} and J. P{\'a}l and Ferenc Gallyas",
year = "2009",
language = "English",
isbn = "9780791843215",
pages = "1061--1062",
booktitle = "Proceedings of the ASME Summer Bioengineering Conference, SBC2008",
edition = "PART B",

}

TY - GEN

T1 - Finite element analysis of a close head axonal injury model - Relating brain tissue biomechanics to skull deformation

AU - Mao, Haojie

AU - Zhang, Liying

AU - Yang, King H.

AU - King, Albert I.

AU - Pál, J.

AU - Gallyas, Ferenc

PY - 2009

Y1 - 2009

N2 - Biomechanical responses of a rat brain in a new weight-drop model were investigated by comparing histological results against finite element model predictions. This graded axonal injury rat model differed from others because of its utilization of intact skull without global angular motion to confound data analyses. Results demonstrated that the maximum principal strain and the compressive strain along the impact direction best correlated the experimentally observed injury locations while the shear strain did not have positive correlation.

AB - Biomechanical responses of a rat brain in a new weight-drop model were investigated by comparing histological results against finite element model predictions. This graded axonal injury rat model differed from others because of its utilization of intact skull without global angular motion to confound data analyses. Results demonstrated that the maximum principal strain and the compressive strain along the impact direction best correlated the experimentally observed injury locations while the shear strain did not have positive correlation.

UR - http://www.scopus.com/inward/record.url?scp=77952664724&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952664724&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9780791843215

SP - 1061

EP - 1062

BT - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

ER -