Fine needle aspiration versus open biopsy for testicular sperm recovery

A controlled study in azoospermic patients with normal spermatogenesis

Herman Tournaye, Koen Clasen, Ayse Aytoz, P. Nagy, André Van Steirteghem, Paul Devroey

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

This retrospective controlled study aimed at comparing two techniques for recovering tessticular spermatozoa in azoospermic patients undergoing intracytoplasmic sperm injection (ICSI). 102 men suffering from infertility because of obstructive azoospermia had ICSI using testicular spermatozoa recovered either by open excisional biopsy (n = 51), or by fine needle aspiration (FNA) (n = 51). A higher average number of spermatozoa were recovered after open biopsy than after FNA, but no significant differences in either fertilization rates or cleavage rates were observed after ICSI with spermatozoa retrieved by the two techniques. Neither was there any significant difference in ongoing pregnancy and implantation rates: in the FNA group, these figures were respectively 19.6% per cycle and 7.8% per embryo transferred and in the open biopsy group 21.6 and 7.1%. We conclude that ICSI with testicular spermatozoa recovered by FNA yields results comparable to those obtained with spermatozoa recovered by open biopsy in azoospermic patients with normal spermatogenesis. However a prospective study is needed to confirm the present results and to assess recovery rates and patient comfort for the two methods.

Original languageEnglish
Pages (from-to)901-904
Number of pages4
JournalHuman Reproduction
Volume13
Issue number4
DOIs
Publication statusPublished - 1998

Fingerprint

Spermatogenesis
Fine Needle Biopsy
Spermatozoa
Intracytoplasmic Sperm Injections
Biopsy
Azoospermia
Pregnancy Rate
Fertilization
Infertility
Embryonic Structures
Retrospective Studies
Prospective Studies

Keywords

  • Azoospermia
  • Fine needle aspiration
  • Intracytoplasmic sperm injection
  • Testicular spermatozoa
  • Testis biopsy

ASJC Scopus subject areas

  • Physiology
  • Developmental Biology
  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Fine needle aspiration versus open biopsy for testicular sperm recovery : A controlled study in azoospermic patients with normal spermatogenesis. / Tournaye, Herman; Clasen, Koen; Aytoz, Ayse; Nagy, P.; Van Steirteghem, André; Devroey, Paul.

In: Human Reproduction, Vol. 13, No. 4, 1998, p. 901-904.

Research output: Contribution to journalArticle

Tournaye, Herman ; Clasen, Koen ; Aytoz, Ayse ; Nagy, P. ; Van Steirteghem, André ; Devroey, Paul. / Fine needle aspiration versus open biopsy for testicular sperm recovery : A controlled study in azoospermic patients with normal spermatogenesis. In: Human Reproduction. 1998 ; Vol. 13, No. 4. pp. 901-904.
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