Tizenöt év alatt szerzett tapasztalataink a primer hyperparathyreosis sebészi kezelésében.

Translated title of the contribution: Fifteen years experience in the surgical treatment of primary hyperparathyroidism

C. Berczi, I. Garai, E. Horkay, L. Galuska, G. Balázs, G. Lukács

Research output: Contribution to journalArticle

Abstract

We measured the efficacy of preoperative localization techniques and results of parathyroidectomy in patients with primary hyperparathyroidism (HPT). From 1986 to 2001, 92 patients were treated with primary HPT. Preoperative localization technique was used in all patients (US n = 85, Tc-99m-sestamibi/Tc-99m-pertechnetate subtraction scintigraphy n = 67, CT n = 18, MRI n = 14) to visualize the abnormal parathyroids. Results of localization studies were compared with surgical and pathological findings. Bilateral neck exploration was carried out in each patient for the identification of all parathyroid glands. If parathyroid adenoma was diagnosed, exstirpation of the abnormal parathyroid was performed. If diffuse hyperplasia was diagnosed, subtotal parathyroidectomy (3 1/2) was performed. The overall sensitivity was 94% for scintigraphy, 74% for US, 67% for CT and 50% for MRI. The PPV was 97% for scintigraphy, 92% for US, 100% for CT and for MRI. At surgery 66 patients had single adenomas and 3 patients had double adenomas. Diffuse hyperplasia was diagnosed in 21 and parathyroid carcinoma was found in 2 patients. Persistent HPT was noted in 1 patient. Recurrent HTP occurred 4 times. After a second operation their HPT disappeared. In conclusion, the sensitivity of Technetium-99m-sestambi and Technetium-99m-pertechnetate subtraction scanning was significantly superior compared to other localization methods. The use of these sensitive preoperative technique can improve the success rate, and decrease the incidence of persistent and recurrent HPT.

Original languageHungarian
Pages (from-to)351-355
Number of pages5
JournalMagyar sebészet
Volume54
Issue number6
Publication statusPublished - 2001

Fingerprint

Primary Hyperparathyroidism
Hyperparathyroidism
Radionuclide Imaging
Sodium Pertechnetate Tc 99m
Parathyroid Neoplasms
Parathyroidectomy
Technetium
Therapeutics
Adenoma
Hyperplasia
Parathyroid Glands
Neck
Incidence

Cite this

Berczi, C., Garai, I., Horkay, E., Galuska, L., Balázs, G., & Lukács, G. (2001). Tizenöt év alatt szerzett tapasztalataink a primer hyperparathyreosis sebészi kezelésében. Magyar sebészet, 54(6), 351-355.

Tizenöt év alatt szerzett tapasztalataink a primer hyperparathyreosis sebészi kezelésében. / Berczi, C.; Garai, I.; Horkay, E.; Galuska, L.; Balázs, G.; Lukács, G.

In: Magyar sebészet, Vol. 54, No. 6, 2001, p. 351-355.

Research output: Contribution to journalArticle

Berczi, C, Garai, I, Horkay, E, Galuska, L, Balázs, G & Lukács, G 2001, 'Tizenöt év alatt szerzett tapasztalataink a primer hyperparathyreosis sebészi kezelésében.', Magyar sebészet, vol. 54, no. 6, pp. 351-355.
Berczi, C. ; Garai, I. ; Horkay, E. ; Galuska, L. ; Balázs, G. ; Lukács, G. / Tizenöt év alatt szerzett tapasztalataink a primer hyperparathyreosis sebészi kezelésében. In: Magyar sebészet. 2001 ; Vol. 54, No. 6. pp. 351-355.
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