Fibronectin on the surface of human lymphocytes

K. Cseh, Lajos Jakab, Judit Török, L. Kalabay, József Marticsek, Terézia Pozsonyi, Szabolcs Benedek

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Fibronectin was detected by immunofluorescence technique on the surface of one part of separated normal peripheral blood lymphocytes by using FITC-conjugated anti-human fibronectin antibodies. Approximately one-fifth of isolated B cells and 7% of O cells contained surface-bound fibronectin but T cells failed to stain. There were no detectable free receptors for fibronectin on the surface of lymphocytes of different subsets as it was studied with FITC-labelled purified fibronectin. The percent of B and O cells bearing surface bound fibronectin was markedly decreased in patients with acute and chronic lymphocytic leukemias.

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalImmunology Letters
Volume9
Issue number6
DOIs
Publication statusPublished - 1985

Fingerprint

Fibronectins
Lymphocytes
Fluorescein-5-isothiocyanate
Fibronectin Receptors
Lymphocyte Subsets
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Fluorescent Antibody Technique
B-Lymphocytes
Coloring Agents
T-Lymphocytes
Antibodies

Keywords

  • fibronectin
  • immunofluorescence technique
  • lymphocytes
  • membrane receptors

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Cseh, K., Jakab, L., Török, J., Kalabay, L., Marticsek, J., Pozsonyi, T., & Benedek, S. (1985). Fibronectin on the surface of human lymphocytes. Immunology Letters, 9(6), 301-305. https://doi.org/10.1016/0165-2478(85)90053-7

Fibronectin on the surface of human lymphocytes. / Cseh, K.; Jakab, Lajos; Török, Judit; Kalabay, L.; Marticsek, József; Pozsonyi, Terézia; Benedek, Szabolcs.

In: Immunology Letters, Vol. 9, No. 6, 1985, p. 301-305.

Research output: Contribution to journalArticle

Cseh, K, Jakab, L, Török, J, Kalabay, L, Marticsek, J, Pozsonyi, T & Benedek, S 1985, 'Fibronectin on the surface of human lymphocytes', Immunology Letters, vol. 9, no. 6, pp. 301-305. https://doi.org/10.1016/0165-2478(85)90053-7
Cseh, K. ; Jakab, Lajos ; Török, Judit ; Kalabay, L. ; Marticsek, József ; Pozsonyi, Terézia ; Benedek, Szabolcs. / Fibronectin on the surface of human lymphocytes. In: Immunology Letters. 1985 ; Vol. 9, No. 6. pp. 301-305.
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