Fibronectin in cryoimmunoglobulinaemias.

K. Cseh, L. Jakab, J. Tôrôk, L. Kalabay, J. Marticsek, S. Benedek, T. Pozsonyi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Isolated and washed cryoimmunoglobulins from 15 patients were studied for the presence of fibronectin by immunodiffusion tests. Two of the isolated cryoglobulins proved to the pure monoclonal immunoglobulins (IgGl kappa and IgGl lambda), nine contained both monoclonal IgM kappa and polyclonal IgG and four were composed of polyclonal IgG, IgM and IgA by immunoelectrophoresis. Double immunodiffusion analysis detected the presence of fibronectin in each of the separated cryoimmunoglobulins. In a solid phase radioimmunoassay, I125 labelled purified fibronectin proved to bind to isolated human monoclonal myeloma proteins of IgGl kappa and IgG3 lambda subclasses. Fibronectin seems to be present not only in mixed polyclonal but also in mixed monoclonal-polyclonal and in monocomponent cryoimmunoglobulins, and it may be bound to one of the immunoglobulin components of the cryoglobulins.

Original languageEnglish
Pages (from-to)483-488
Number of pages6
JournalAllergologia et Immunopathologia
Volume12
Issue number6
Publication statusPublished - Nov 1984

Fingerprint

Fibronectins
Cryoglobulins
Immunoglobulin G
Immunodiffusion
Immunoglobulin M
Immunoglobulins
Myeloma Proteins
Immunoelectrophoresis
Immunoglobulin A
Radioimmunoassay

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Cseh, K., Jakab, L., Tôrôk, J., Kalabay, L., Marticsek, J., Benedek, S., & Pozsonyi, T. (1984). Fibronectin in cryoimmunoglobulinaemias. Allergologia et Immunopathologia, 12(6), 483-488.

Fibronectin in cryoimmunoglobulinaemias. / Cseh, K.; Jakab, L.; Tôrôk, J.; Kalabay, L.; Marticsek, J.; Benedek, S.; Pozsonyi, T.

In: Allergologia et Immunopathologia, Vol. 12, No. 6, 11.1984, p. 483-488.

Research output: Contribution to journalArticle

Cseh, K, Jakab, L, Tôrôk, J, Kalabay, L, Marticsek, J, Benedek, S & Pozsonyi, T 1984, 'Fibronectin in cryoimmunoglobulinaemias.', Allergologia et Immunopathologia, vol. 12, no. 6, pp. 483-488.
Cseh K, Jakab L, Tôrôk J, Kalabay L, Marticsek J, Benedek S et al. Fibronectin in cryoimmunoglobulinaemias. Allergologia et Immunopathologia. 1984 Nov;12(6):483-488.
Cseh, K. ; Jakab, L. ; Tôrôk, J. ; Kalabay, L. ; Marticsek, J. ; Benedek, S. ; Pozsonyi, T. / Fibronectin in cryoimmunoglobulinaemias. In: Allergologia et Immunopathologia. 1984 ; Vol. 12, No. 6. pp. 483-488.
@article{7fc111d7853f44d69257b436c45ad86a,
title = "Fibronectin in cryoimmunoglobulinaemias.",
abstract = "Isolated and washed cryoimmunoglobulins from 15 patients were studied for the presence of fibronectin by immunodiffusion tests. Two of the isolated cryoglobulins proved to the pure monoclonal immunoglobulins (IgGl kappa and IgGl lambda), nine contained both monoclonal IgM kappa and polyclonal IgG and four were composed of polyclonal IgG, IgM and IgA by immunoelectrophoresis. Double immunodiffusion analysis detected the presence of fibronectin in each of the separated cryoimmunoglobulins. In a solid phase radioimmunoassay, I125 labelled purified fibronectin proved to bind to isolated human monoclonal myeloma proteins of IgGl kappa and IgG3 lambda subclasses. Fibronectin seems to be present not only in mixed polyclonal but also in mixed monoclonal-polyclonal and in monocomponent cryoimmunoglobulins, and it may be bound to one of the immunoglobulin components of the cryoglobulins.",
author = "K. Cseh and L. Jakab and J. T{\^o}r{\^o}k and L. Kalabay and J. Marticsek and S. Benedek and T. Pozsonyi",
year = "1984",
month = "11",
language = "English",
volume = "12",
pages = "483--488",
journal = "Allergologia et Immunopathologia",
issn = "0301-0546",
publisher = "Ediciones Doyma, S.L.",
number = "6",

}

TY - JOUR

T1 - Fibronectin in cryoimmunoglobulinaemias.

AU - Cseh, K.

AU - Jakab, L.

AU - Tôrôk, J.

AU - Kalabay, L.

AU - Marticsek, J.

AU - Benedek, S.

AU - Pozsonyi, T.

PY - 1984/11

Y1 - 1984/11

N2 - Isolated and washed cryoimmunoglobulins from 15 patients were studied for the presence of fibronectin by immunodiffusion tests. Two of the isolated cryoglobulins proved to the pure monoclonal immunoglobulins (IgGl kappa and IgGl lambda), nine contained both monoclonal IgM kappa and polyclonal IgG and four were composed of polyclonal IgG, IgM and IgA by immunoelectrophoresis. Double immunodiffusion analysis detected the presence of fibronectin in each of the separated cryoimmunoglobulins. In a solid phase radioimmunoassay, I125 labelled purified fibronectin proved to bind to isolated human monoclonal myeloma proteins of IgGl kappa and IgG3 lambda subclasses. Fibronectin seems to be present not only in mixed polyclonal but also in mixed monoclonal-polyclonal and in monocomponent cryoimmunoglobulins, and it may be bound to one of the immunoglobulin components of the cryoglobulins.

AB - Isolated and washed cryoimmunoglobulins from 15 patients were studied for the presence of fibronectin by immunodiffusion tests. Two of the isolated cryoglobulins proved to the pure monoclonal immunoglobulins (IgGl kappa and IgGl lambda), nine contained both monoclonal IgM kappa and polyclonal IgG and four were composed of polyclonal IgG, IgM and IgA by immunoelectrophoresis. Double immunodiffusion analysis detected the presence of fibronectin in each of the separated cryoimmunoglobulins. In a solid phase radioimmunoassay, I125 labelled purified fibronectin proved to bind to isolated human monoclonal myeloma proteins of IgGl kappa and IgG3 lambda subclasses. Fibronectin seems to be present not only in mixed polyclonal but also in mixed monoclonal-polyclonal and in monocomponent cryoimmunoglobulins, and it may be bound to one of the immunoglobulin components of the cryoglobulins.

UR - http://www.scopus.com/inward/record.url?scp=0021525088&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021525088&partnerID=8YFLogxK

M3 - Article

VL - 12

SP - 483

EP - 488

JO - Allergologia et Immunopathologia

JF - Allergologia et Immunopathologia

SN - 0301-0546

IS - 6

ER -