Fibronectin in bronchoalveolar lavage fluid and plasma of dogs with acute inflammation of the lungs

B. NAGY, KATONA, J. ERDEI, L. KARMAZSIN, J. FACHET

Research output: Contribution to journalArticle

Abstract

Bronchoalveolar inflammation, which was generated in dogs by Broncho‐Vaxom instilled into the right lower lobe, was characterized first of all by an increased influx of macrophages. In this nonpurulent acute‐subacute inflammatory reaction, the lavage fibronectin decreased rapidly three hours after the incubation and then a marked gradual elevation was observed, which persisted throughout the whole two‐week process, while plasma fibronectin concentrations were not altered significantly. Changes in the levels of lavage fibronectin may be an important sign for the control of the inflammatory reaction activity in the lungs.

Original languageEnglish
Pages (from-to)387-390
Number of pages4
JournalAPMIS
Volume99
Issue number1-6
DOIs
Publication statusPublished - Jan 1991

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Keywords

  • Broncho‐Vaxom®
  • Fibronection
  • bronchoalveolar lavage
  • inflammation

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Immunology and Allergy
  • Microbiology (medical)

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