Fibrinolytic activity in rat anaphylaxis

L. Fésüs, E. Olveti, B. Csaba, L. Muszbek

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Abstract

The activity of fibrinolytic system measured by different methods and the concentration of plasma fibrinogen were determined in rats suffering mild or severe active anaphylactic shock. In severe anaphylactic shock of Bordetella Pertussis Vaccine pretreated animals, the plasminogen activator content was markedly enhanced and the fibrinolytic activity significantly increased; however, the total inhibitor capacity did not change. The fall in fibrinogen concentration was only moderate. Similar but minor enhancement of fibrinolysis could be observed in mild anaphylaxis. The results suggest that the activated plasminogen plasmin system may contribute to the development of severe anaphylactic outcome in the rat. The possible pathogenic mode is discussed.

Original languageEnglish
Title of host publicationTHROMB.DIATHES.HAEMORRH.
Pages341-349
Number of pages9
Volume32
Edition2-3
Publication statusPublished - 1974

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Anaphylaxis
Fibrinogen
Pertussis Vaccine
Bordetella pertussis
Plasminogen Activators
Plasminogen
Fibrinolysin
Fibrinolysis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fésüs, L., Olveti, E., Csaba, B., & Muszbek, L. (1974). Fibrinolytic activity in rat anaphylaxis. In THROMB.DIATHES.HAEMORRH. (2-3 ed., Vol. 32, pp. 341-349)

Fibrinolytic activity in rat anaphylaxis. / Fésüs, L.; Olveti, E.; Csaba, B.; Muszbek, L.

THROMB.DIATHES.HAEMORRH.. Vol. 32 2-3. ed. 1974. p. 341-349.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fésüs, L, Olveti, E, Csaba, B & Muszbek, L 1974, Fibrinolytic activity in rat anaphylaxis. in THROMB.DIATHES.HAEMORRH.. 2-3 edn, vol. 32, pp. 341-349.
Fésüs L, Olveti E, Csaba B, Muszbek L. Fibrinolytic activity in rat anaphylaxis. In THROMB.DIATHES.HAEMORRH.. 2-3 ed. Vol. 32. 1974. p. 341-349
Fésüs, L. ; Olveti, E. ; Csaba, B. ; Muszbek, L. / Fibrinolytic activity in rat anaphylaxis. THROMB.DIATHES.HAEMORRH.. Vol. 32 2-3. ed. 1974. pp. 341-349
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