A fibrinolysis vizsgálata in vitro alvadékoldási teszt segítségével polycythaemia verában.

Translated title of the contribution: Fibrinolysis studied by an in vitro clot lysis test in polycythemia vera

E. Pósán, G. Ujj, A. Kiss, B. Telek, K. Rák, M. Udvardy

Research output: Contribution to journalArticle

Abstract

Results obtained by a simple in vitro clot lysis test in polycythemia vera, polyglobulia, essential thrombocythemia and chronic immun thrombocytopenic purpura are reported. Increased lysis resistance of the platelet-rich clots was demonstrated in polycythemia and essential thrombocythemia, ostensibly caused by the high plasma level of plasminogen activator inhibitor-1. Following retraction of platelet-rich clots no further increase of lysis-resistance occurred in polycythemia and essential thrombocythemia. This phenomenon is most likely due to abnormal platelet function. The well known thromboembolic complications may at least partly result from the impaired fibrinolysis in diseases with high platelet counts.

Translated title of the contributionFibrinolysis studied by an in vitro clot lysis test in polycythemia vera
Original languageHungarian
Pages (from-to)71-74
Number of pages4
JournalOrvosi hetilap
Volume137
Issue number2
Publication statusPublished - Jan 14 1996

ASJC Scopus subject areas

  • Medicine(all)

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